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Acivir (Acyclovir)
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Acivir

Acivir is an antiviral medication that stops a protein (an enzyme called DNA polymerase) in the herpes simplex virus (HSV) and varicella-zoster virus (VZV). Without this enzyme, the virus can't make copies of itself.

Other names for this medication:
Acirax, Acivir, Aclovir, Acvirax, Acycloguanosine, Acyclor, Acyclovir, Acylab, Alovir, Cevirin, Civir, Cloviderm, Clovir, Clovirax, Cutivir, Cycloex, Cyclopiz, Docvir, Herperax, Herpex, Herpovir, Herzovir, Kayvir, Lovir, Lyrovir, Nisivir, Ocurax, Ocuvir, Ophtrhovir, Optiviral, Oveer, Psyvir, Ridoherp, Rivol, Rovir, Rowapil, Setuvir, Spaclovir, Trikase, Virclo, Viroderm, Viroxit, Virucid, Vivorax, Zovir

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Also known as: Acyclovir

Description

Acivir (acyclovir) is an antiviral drug. Acyclovir slows the growth and spread of the herpes virus in the body.

Acivir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox.

Acivir will not cure herpes, but it can lessen the symptoms of the infection.

Dosage

Take Acivir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Start taking Acivir as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Acyclovir doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

Drink plenty of water while you are taking Acivir to keep your kidneys working properly.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses may increase the risk of your virus becoming resistant to medication.

Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

Store at room temperature away from moisture and heat.

Detailed Acivir dosage information

Overdose

An overdose of Acivir Topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Acivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Here, we studied the role of RAGE and expression of its proinflammatory ligands, EN-RAGEs (S100/calgranulins), in inflammatory events mediating cellular activation in diabetic tissue. Trophoblastic neoplasms express fatty acid synthase, which may be a therapeutic target via its inhibitor C93. Then it propagates the deformation into the whole volume through the use of a tetrahedral mesh and it finishes the registration using a mutual information based optical flow. In addition, the endocrine-disrupting effects of TCDD are, at least in part, caused by the direct action on the LH receptor expression on granulosa cells. FDG-PET as a potential tool for selecting patients with advanced non-small cell lung cancer who may be spared maintenance therapy after first-line chemotherapy. First-principles calculations on supercells matching the experimental compositions predicted a systematic charge redistribution in the nearest-neighbor shell around the solute atoms, also following the Pauling and Watson electronegativity scales.

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Several studies suggest a functional role for neuronal nitric oxide synthase (nNOS) in the development or maintenance of neuropathic pain, but such a contribution remains unclear. A two-stage analysis was developed to quantify the change in pregnancy length after maternal exposure to extreme heat conditions adjusted for a range of covariates. The strictures were opened with endobronchial stents but became obstructed again by inflammatory granulation tissue overgrowth through the stent mesh. Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding. SnoN recruits transcriptional repressor complex to block Smad-dependent transcriptional activation of TGF-beta-responsive genes. This evaluation is especially relevant when quality of care is considered.

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A postoperative rise in liver function tests is expected, reflecting the liver injury response to RFA. Hematuria and dysuria in the self-diagnosis of urinary schistosomiasis among school-children in Northern Cameroon. The activated partial thromboplastin time waveform is abnormal in children with meningococcal disease and may be a useful adjunct in the diagnosis and management of sepsis in children. West Nile virus (WNV) infection causes a life-threatening meningoencephalitis that becomes increasingly more prevalent over the age of 50 and is 40-50x more prevalent in people over the age of 70, compared with adults under the age of 40. These data give promising indications that oral human IgG might represent an alternative approach for immunosuppressive B-cell targeted therapies in RA. Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.

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The present results are consistent with the view that emotions trigger adaptive action tendencies independently of task settings. Over a 6-month period, 65 patients (34 affected by a solid tumor, 31 by a hematological disorder) were enrolled. Neuroticism proved to be not associated with the 5-HTT genotype. The ultrastructure of both these cell groups has been described. Bilateral paravertebral block anesthesia for thymectomy by video-assisted thoracoscopy in patients with myasthenia gravis. Determining individual muscles forces from human performance has greatly depended on the quality of inverse dynamics solutions, as muscle force decomposition remains the only feasible approach for determining muscle forces non-invasively in human movement. Comparison of responses of ventral posterolateral and posterior complex thalamic neurons in naive rats and rats with hindpaw inflammation: mu-opioid receptor mediated inhibitions. Although I domain-deleted LFA-1 (DeltaI-LFA-1) cannot bind ligand, it is able to signal constitutively into the cell. LPS induced the activation of NF-kappaB in a dose-dependent manner, but BAC from smokers were approximately 10 times more sensitive, and showed faster kinetics of activation of NF-kappaB than BAC from nonsmokers.

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Vulnerability to schizophrenia: neuropsychological performance and schizotypal personality traits. Serial prealbumin levels as predictors of outcomes in a retrospective cohort of peritoneal and hemodialysis patients. CryIAc toxin bound strongly to APN, while either the structurally related CryIAa and CryIAb toxins or CryIC, CryIIA, and CryIIIA toxins showed weak binding to APN. We studied whether knockdown of Cldn3 and/or Cldn4 expression using RNA interference influenced CPE-mediated cytotoxicity. It is unknown exactly why this medial tissue mass forms and what cells are involved in its formation. Recent evidence from studies of postmenopausal HRT in healthy women demonstrated a short-time increased risk of coronary heart disease. All sealed endoleaks are not the same: a treatment strategy based on an ex-vivo analysis. PC-3, LNCaP and DU-145 human prostate cancer cells were infected with a retrovirus encoding a dominant-negative version of the catalytic subunit of telomerase (DN-hTERT). This newly acquired data may provide important information to fisheries managers of the East Coast. The HsRad51-overexpressing cells showed decreased plating efficiency and growth rate in a dose-dependent manner with regard to the degree of overexpression.

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Transarterial embolization for ruptured hepatocellular carcinoma: survival predictors. Pregnant women should be repeatedly recommended to take folic acid supplements of 400 microg/day. At the other end of the pediatric spectrum, adolescent athletes seeking to enhance their performance are consuming poorly studied sports supplements that may not be beneficial and may even be toxic. The authors assessed the efficacy and safety of intravenous lomir used to treat arterial hypertension in 10 coronary patients early after aortocoronary shunting. MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. Municipal solid waste landfills are sources of air pollution that may affect the health and quality of life of neighboring communities. Heart homogenates from adult chicks catabolize glucose almost entirely by the glycolytic-Krebs cycle pathway, with negligible participation by the phosphogluconate pathway. Helper virus-free vector stocks were initially evaluated in vitro for their capacity to direct expression of NT-3 mRNA and protein.

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Oral administration of type II collagen suppresses non-specifically induced chronic arthritis in rats. News Briefs: The number of people living in countries facing severe water shortages will increase more than four-fold over the next 25 years. It is mobilized when the animal is mechanically stimulated, resulting in the discharge of a few white filaments, the tubules. These results suggest that placebo analgesia has its effect under the resting condition and MPFC, IPL and PPC may have an important role in placebo analgesia. Much progress has been made in understanding the biology and pathogenesis of this important feline virus. Deletion of a single Dll4 allele or pharmacologic inhibition of Dll4/Notch signaling by intraocular administration of either soluble Dll4-Fc or a blocking antibody against Dll4 all produced the same set of characteristic abnormalities in the developing retinal vasculature, most notably enhanced angiogenic sprouting and increased endothelial cell proliferation, resulting in the formation of a denser and more highly interconnected superficial capillary plexus.

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All ferrets that received m102.4 ten hours following a high dose oral-nasal Nipah virus challenge were protected from disease while all controls died. Comparison of plasma steroid and gonadotrophin profiles in spontaneous cycles in which conception did and did not occur. To verify whether this difference in the epidemiological profile is still observed today, we analysed renal stones collected in various regions of the globe and compared their composition to that of stones observed in France. Dysferlin deficiency and the development of cardiomyopathy in a mouse model of limb-girdle muscular dystrophy 2B. From an evaluation of the anatomic and biomechanical features of the mandible, we propose the notion of a useful zone for fixation. The alleles from different clusters showed high sequence divergences, indicated by various SNPs and InDels (insertion/deletion). CRMP-5-IgG in patient with paraneoplastic optic neuritis with lung adenocarcinoma.

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Of these, eight were predicted to be involved in the formation of the flagella apparatus, and the decreased expression is likely to be responsible for the reduced motility and ability to autoagglutinate that was observed for hspR mutant cells. Alignment of the NS3 sequences from the attenuated BTV 4 vaccine strain and the field strains showed 13 aa substitutions, which may, either singularly or together, be responsible for attenuation and hence determining the virulence of the virus. Ageing changes in the liver of two Poeciliid fishes, the guppy Poecilia (Lebistes) reticulata and the Amazon molly, P. The first step in the generation of a malignancy seems to be a transformation in the genetic apparatus of a single cell. Temperature sensitivity of calcium binding for parvalbumins from Antarctic and temperate zone teleost fishes. Because heart failure is difficult to diagnose accurately on the basis of the history and physical examination alone, It is vital that clinical evaluation such as echocardiography be used to confirm the diagnosis. Our data using ultrasonographic technique agree well with previous studies using other devices.

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Plasma assay results for prothrombin time and activated partial thromboplastin time obtained on the fully automated Dade Auto-FI were compared with those obtained on the more traditional semi-automated Bio-Quest Fibrometer. Gene expression of cytokines/receptors of the IL-6 family was documented in myocardial samples using cDNA array hybridization and RNase protection assays. The purpose of this review is to briefly summarize current knowledge of fetal and neonatal thyroid function, and then to summarize the most significant new findings over the last year that add to our knowledge of the cause, diagnosis, and management of fetal and neonatal thyroid disorders. It may also provide new ways to measure SC water uptake and water holding capacity following application of products. NG-nitro-L-arginine-methyl-ester, NG-monomethyl-L-arginine, or N-iminoethyl-L-ornithine was given at various concentrations, intraperitoneally, one hour before bacterial challenge. Details of individual PUs were described by sketching the PU photograph and categorized to characterize the morphology of PUs.

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RNA interference (RNAi) of LjCLV3 caused enlargement of not only the SAM, but also the primary and secondary inflorescence meristems (IMs). Effects of cinacalcet in renal transplant patients with hyperparathyroidism bactrim 400-80mg tab . Provider perceptions of the social work environment and the state of pediatric care in a downsized urban public academic medical center. Private HD patients are older and less likely to be diabetic than public patients. Autopsy showed large necrotic mass (19 x 14 x 8.0 cm) surrounding the terminal ileum with multiple smaller nodules on the omentum and mesentery. It is assumed that images are only of relative translation and rotation.

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Photochemical decontamination of platelet concentrates (PCs) has been demonstrated by the use of 8-methoxypsoralen and ultraviolet A light. An estimated 80 million (nearly one in three) Americans have cardiovascular disease, which is the leading cause of morbidity and mortality worldwide. We evaluated adherence to the NNR in relation to prostate cancer (PC) in Swedish men, including potential interaction with a genetic risk score and with lifestyle factors. Human gastric epithelial cells (MKN 28) were incubated with undialyzed or dialyzed broth culture filtrates from wild-type H. The 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione scaffold have found many applications in recent years. A few years ago, a new long-pulsed tunable dye laser (LPTDL, 1.5 ms) was introduced for the treatment of leg veins. Comparative genomics, genosystematics and scientific school of A. Samples were obtained at diagnosis, after glucocorticoid (GC) therapy, during the induction phase with L-ASP, vincristine (VCR) and adriamycin (ADR), during the re-induction and within the week after treatment. One-way Analysis of Variance followed by Tukey-Kramer multiple comparison test was used for comparison of incubation period, xanax drug names duration of hospital stay, and cost of management. The in vitro titration test as presented is a more sensitive method than animal inoculation.

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The factor structure of the working alliance inventory in cognitive-behavioral therapy. Risks to health among American Indian/Alaska Native high school students in the United States. This is the first demonstration of phosphorylation of CAP by any kinase. CFTR bioassays in the nasal epithelium (nasal potential difference measurements) and the rectal mucosa (intestinal current measurements) are discussed in detail including efforts to standardize the techniques across Europe. The combination of the attractants did not enhance their efficiency. Immunohistological study of interferon-gamma- and interleukin-4-bearing cells in human periodontitis gingiva. The combined use of a biosurfactant and an enzyme preparation to treat an effluent with a high fat content. Five hundred and fifty three GPs included 1042 patients presenting with acute maxillary sinusitis in the study from December 2000 to July 2001.

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Two coxsackievirus B4 (CVB4) vaccine vectors were designed to induce HIV-specific B or T cell responses. EXPERIMENTAL-MICROSCOPIC STUDY ON THE PROBLEM OF THE LOCALIZATION OF RESIDUAL HEARING DISORDERS AFTER INDUSTRIAL NOISE WITH TONAL SOUND COMPONENTS. Vitiligo is an acquired skin disorder with a great social impact. GES decreases the proximal gastric tone in an energy-dependent manner. Embryonic stem cells in the treatment of severe cardiac insufficiency. Based on the linear stability of period-one and period-two orbits of the coupled maps, we construct coherent states in which the degrees of freedom are synchronized and the mean-field stays nearly fixed.

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The diagnostic performance of each one of the different types of biopsy varies widely. Breast cancer outcome, including response to therapy, risk of metastasis and survival, is difficult to predict using currently available methods, highlighting the urgent need for more informative biomarkers. The case of pleural tuberculosis revealing AIDS presented here illustrates the difficulties of management of this co-infection due to polychemotherapy used to treat each of these pathologies causing drug interactions requiring dose adjustments and changes in treatment protocol and an increase in side effects. The ability of nanoparticles to exacerbate pre-existing inflammatory disorders is not well documented for engineered nanoparticles, and is certainly lacking for CeO(2) nanoparticles. Good analytical results improved still further when this correction method was used. Although they have characteristics in common, the anticonvulsants currently used are quite diverse and vary in their spectrum of activity, quality of supporting evidence, and organ toxicities. The breakdown of the dye under pulsed laser irradiation was studied and the energy under which this effect occurs was calculated for the wavelength of 532 nm. Multiple logistic regression analyses were conducted to determine the effects of work conditions and social relationships on the mental health of prison staff.

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Electron emission from individual indium arsenide semiconductor nanowires. A novel pathway of NADPH oxidase/vascular peroxidase 1 in mediating oxidative injury following ischemia-reperfusion. Local maternal control of seed size by KLUH/CYP78A5-dependent growth signaling. For subsequent analysis of embryonic samples it was necessary to adjust the amounts of competitor oligonucleotides, as the expression levels of several genes differed to a large extent between adult and embryonic bactrim and alcohol experience tissues. ON A CASE OF HEMOLYTIC ANEMIA DUE TO SULFAMETHOXYPYRIDAZINE IN A SUBJECT WITH ERYTHROCYTE GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY. Poly(L-lactic acid)/hydroxyapatite hybrid nanofibrous scaffolds prepared by electrospinning. This article intends to provide an overview of the current state of knowledge on the spread of scrapie, chronic wasting disease, bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease agents through the body in naturally affected hosts, and in model animals experimentally challenged via the alimentary tract.

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