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Actocard

Actocard is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. Actocard among others, is a selective β₁ receptor blocker medication.

Other names for this medication:
Actiblok, Actocard, Betaloc, Dutoprol, Intramet, Macsart, Mepol, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Supermet, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol

Description

Metoprolol injection is used to reduce the risk of death from an acute heart attack. It is given to people who have already had a heart attack.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metoprolol. It may not be specific to Actocard. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.

Swallow the extended-release capsule and tablet whole. Do not crush, break, or chew them.

If you cannot swallow the extended-release capsule:

You may open it and sprinkle the contents over a small amount (teaspoonful) of soft food (including applesauce, pudding, or yogurt). Swallow the mixture within 60 minutes. Do not store for later use. You may also use a nasogastric tube to give the medicine. Mix the contents of the opened capsule with water into a syringe. Gently shake the mixture for about 10 seconds, then flush it through the tube. Rinse the tube with water until all of the medicine is washed out.

Take the tablet or extended-release tablet with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute heart attack or heart failure: For oral dosage form (extended-release capsules): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg 2 times a day. The medicine will be started in the hospital. Children—Use and dose must be determined by your doctor. For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight once a day. The first dose should not be more than 50 mg once a day. Your doctor may adjust your dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day. Children—Use and dose must be determined by your doctor. .

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heart rate, trouble breathing, or fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Actocard dosage information

Side effects

The most common side effects associated with Actocard are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Tests of forelimb function and asymmetry were administered for 4weeks post-injury. Field defects were frequently incomplete and incongruous, combining central scotomas with elements of homonymous and bitemporal amblyopias. Breast cancer predictive factor testing: the challenges and importance of standardizing tissue handling. The extracellular alpha-subunit of the IGF-I receptor (IGF-IR) contains an IGF-I binding domain, and the beta-subunit possesses tyrosine kinase activity, which is greatly enhanced when IGF-I binds to the alpha-subunit and leads to its autophosphorylation. GRE1 antiserum also inhibits liver invasion in the C170HM2 colorectal liver-metastasis model. The model allows for analog membrane dynamics and an arbitrary number of synaptic connections, each with tunable conductance and reversal potential.

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Dermatologists should screen for PsA in their patients, especially long-standing patients who did not initially present with PsA. Instead, we have identified syntaxin 6 as a component of the core machinery responsible for homotypic ISG fusion. Induction polychemotherapy before radiotherapy in carcinoma of the cavum. The influence of chloramphenicol on the nucleic acids and protein synthesis in five bacterial strains has been studied on the microchip. There were significant associations between diagnosis and the type of aversive stimulation which preceded assaults. Different time scales, associated with fast heterogeneous dynamics inside 2D cages and slower motion of larger parts of the film, can be identified from the correlation functions. A considerable proportion of the Spanish FETP has is provided conventional class room training .

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When p21 expression was inhibited by cycloheximide, galectin-8 directed the cells toward apoptosis, which involves induction of poly(ADP-ribose) polymerase cleavage. Two new detailed methods are presented for the calculation of lateral and dorso-plantar talo-calcaneal overlap in an attempt to better define the talo-calcaneal inter-relationship. It can be suggested that delayed cellular response might indicate restenosis but also can be considered considered as a progression of the original arterial disease. It is not known if feedback can influence the behaviour of supervisors in the grades they award. Subsequently, we turn towards another broad group of theories of consciousness, in the form of electromagnetic field theories.

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The poorer results occurred in patients with severe injuries associated with posterior comminution of the humerus and who required more extensive reconstructive procedures. Food processing by animals: do beavers leach tree bark to improve palatability?. However, the scaffolds fabricated by RP have very smooth surfaces, which tend to discourage initial cell attachment. When we measured lysis as the rate of decrease in turbidity at 350 nm, we found that the rate of lysis was slower than normal for clots with thinner fibers. The present study examined the reliability of the effects of the treatment, and provided an evaluation of the attained levels of reading and spelling by relating them to normal levels. In addition to its role as a potent and selective pulmonary vasodilator, iNO is a useful intraoperative adjunct in adult cardiac surgery patients that may reduce the need for right ventricular assist device placement. We compared the effects of two contrast training programs on a range of measures in high-level rugby union players during the competition season.

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Determination of the vitamin C allowance of the body in overirradiation with ultraviolet radiation. Comparative analysis of the structure and function of the chicken c-myc and v-myc genes: v-myc is a more potent inducer of cell proliferation and apoptosis than c-myc. Normalising impacts in an environmental systems analysis of wastewater systems. This finding underlines the importance of growth hormone in influencing immune system development and further suggests possible autocrine/paracrine regulatory loops in skin tissue. The likelihood of smokers quitting on developing early signs of each condition was determined. Do antibiotics shorten symptoms in patients with purulent nasal discharge?. Density functional theory optimized basis sets for gradient corrected functionals: 3d transition metal systems.

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An illustrative example is given with the well-studied streptavidin-biotin complex. A basic knowledge of how medical negligence is adjudicated in the various judicial courts of India will help a doctor to practice his profession without undue worry about facing litigation for alleged medical negligence. Thus, it alleviates drug craving and impedes relapse of drug use. And the more that is understood of its pathogenesis, the better the prospects for treatment. CONTRIBUTIONS OF CAROTID ANGIOGRAPHY IN SYNCOPE AND ECLYSIS SYNDROMES. We isolated an Arabidopsis ortholog (AtBR6ox gene) of the tomato Dwarf gene. PERFORMANCE DECREMENT IN VIGILANCE, THRESHOLD, AND HIGH-SPEED PERCEPTUAL MOTOR TASKS. However, the same number of years of survival reflects higher relative longevity at older ages than at younger ages. Physiologic alterations of inner ear mechanism such as extra-cerebral changes in conductance or stimulation-dependent depolarization processes in extra-cerebral regions of the auditory system could be possible explanations for the significant difference in measurement parameters.

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Correlation of scalp EEG and 1H-MRS metabolic abnormalities in temporal lobe epilepsy. Structure elucidation was carried out by NMR spectroscopy and chemical correlations to establish absolute configurations. High job stress was associated with greater reports of anger-in and anger-out behavior. Participants who were smoking at 3 months were randomized to an alternative treatment regimen or placebo. One and 3 days and 1, 2, 3, and 4 weeks after surgery, contact between the lens capsule and IOL optic as well as capsule bend formation were evaluated using optical coherence tomography (OCT). Evaluation of isometric antagonist coactivation strategies of electrically stimulated muscles. The effect of different opioids on postoperative nausea and vomiting (PONV) has not been conclusively determined yet, thus the aim of this study was to compare the incidence of PONV in propofol-anaesthetized patients receiving either fentanyl or remifentanil as opioid supplement. The aim of this study was to determine the frequency of adenomas as well as sensitivity, specificity, positive and negative predictive values of FS for polyp screening in two groups of asymptomatic individuals using colonoscopy (CP) as the gold standard. Especially the possibility of using this multi-well-plate together with automated imaging-systems has the great advantage of combining optical and sensory monitoring accessible to high-throughput-applications. The clinical use of bis-(hydroxy-ethyl-thio)-1,10-decane in the treatment of hyperlipemic and dyslipemic conditions.

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Simulation results show that the improved AR estimator can give more accurate estimate of the mean frequency and variance of the blood signal than the conventional one, even if the amplitude of the clutter is very large compared with Doppler signal. Intraspecific incompatibility in the soil bacterium Myxococcus xanthus demonstrates that the social life of microbes is antagonistic on local and global scales. Predictors for response to intermittent androgen deprivation (IAD) in prostate cancer cases with biochemical progression after surgery. The patients were randomly divided into modeling group and model validation group. Marine natural products research: current directions and future potential. New Zealand boat builders and their employees remain at risk for occupational health problems by virtue of their employment.

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The purpose of the present study is to investigate spatial surface electromyography (SEMG) potential distribution pattern in type 2 diabetes mellitus (T2DM) patients. TSF and BMI threshold (cut-off points for overweight and obesity) were defined as 85th and above of age- and gender-specific TSF and BMI standard charts which were based on American representative survey data. The purpose of this article is to explain the effects of glucocorticoid therapy on diabetes management and to demonstrate how to achieve optimal diabetes control through several case studies. TRANSPORT OF SPUTUM SPECIMENS TO A CENTRAL TUBERCULOSIS LABORATORY. However, a sustained increase in abdominal pressure may be life-threatening.

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Tumor-host interaction in non-random metastatic pattern distribution. The aim of the present study was to investigate the distribution of proglucagon mRNA and GLP-1-immunoreactive (GLI) perikarya in various regions of the chick brain. On the occasion of a first visit to the physician, the patient usually presents with nonspecific symptoms, in particular recurrent infections, a challenging situation in terms of making the correct diagnosis. These are in fact identifiable among the forty-one individuals carefully studied. After purification, conjugates were evaluated in a DNA hybridization assay on a microarray, as macromolecules being able to favor capture of the target.

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Thirty studies with 167 cases from 1986 to October 2009 were identified. Different types of small granule-containing cells and neurons in the guinea-pig adrenal medulla. This suggests that programs for prevention of LBW should be tailored according to maternal age, begin before conception, and continue with enhanced surveillance during prenatal visits. Newborn screening coupled with comprehensive follow-up reduced early mortality of sickle cell disease in Connecticut. An algorithm for predicting the expected time on the waiting list for a histocompatible graft was recently introduced. NEFA concentration in the incubation media did not increase in the presence of TGRLs indicating that the effects observed were solely due to intact lipoprotein particles. Generalizability theory was applied to estimate the reliability of the SSAP and to compare it with other procedures carried out in the same populations, such as the rating of application forms and a structured interview procedure.

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Further analysis of the core replication domain identified amino acids that are important for DNA binding by Orc6. Although the major causes of CVD are well documented and explain the majority of cardiovascular deaths, the prevalence of conventional cardiovascular risk factors vary substantially across diverse cultural groups. The objective of this study was to identify physiochemical changes in the surface and bulk properties of explanted polypropylene hernia meshes compared to pristine polypropylene mesh materials. In addition, to determine whether serum allantoin is correlated with reactive oxygen species (ROS) biomarkers, we measured 8-hydroxy deoxyguanosine and 15-F2t-isoprostane, markers of ROS, in urine samples from 30 gout patients before and 1 year after benzbromarone treatment (50 mg/d). Finally, the planned technology transfer to vaccine manufacturers in low and middle-income countries is discussed. Intragastric immunization of the recombinant strain conferred protective immunity against Salmonella infection in mice. These protein structures provide an unprecedented atomic-level understanding of the mechanism governing the exquisite specificity of each receptor.

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PERIPHERAL NEUROPATHY OF THE ALCOHOLIC: I, AETIOLOGICAL ROLE OF ANEURIN AND OTHER B-COMPLEX VITAMINS. Spin-selective Kondo insulator: cooperation of ferromagnetism and the Kondo effect. The Cochrane Airways Group trials register and reference lists of identified articles were searched. The results revealed no difference in the amplitude and latency of early components of the ERP responses between the binocular and fellow eye stimulation. Two distinct growth-promoting signals were used to activate B cells. Complete filling of aneurysmal sac was achieved in other patient but 2 years later will flagyl cure ear infection his aneurysm re-opened and required open surgery treatment. Clinical analysis of laparoscopic and endoscopic cooperative surgery in the treatment of gastric gastrointestinal stromal tumor: report of 46 cases. Completion of an Osteoporosis Knowledge Questionnaire and questions about learning needs and preferences. Biopsy of the skin lesions showed typical LP with no evidence of sarcoid granulomas.

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In ectotherms such as reptiles, however, thermal ecology places an additional constraint on realized locomotor performance. Nursing work and workload concepts and labels are defined and measured in different and often contradictory ways. The application of the PIT model to the Windrush catchment with optimum parameter values was demonstrated. Gonadotropins cross the vascular endothelial barrier to reach their target organs. Furthermore, we show by validation of transcriptome sequencing data that the Phelipanche orthologue of a haustorium-specific Cuscuta gene, which codes for a cysteine proteinase, was activated in the early stages of Phelipanche invasion. Despite advances in understanding and treatment, ovarian vasotec generic equivalent cancer remains a major cause of cancer mortality worldwide.

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Some superelastic wires had torsional moments that were comparable with conventional nickel-titanium wires. Chemical constituents of halophilic facultatively anaerobic bacteria, 1. In this study, the reverse polarization method is implemented using transmit and receive arrays to improve the visibility of the interventional devices. So far, few studies have experimentally tested the causality of this neurontin dose renal relationship and it is not clear what type of manipulation affects drinker prototypes and drinking levels. Effect of recombinant bactericidal/permeability-increasing protein on endotoxin translocation and lipopolysaccharide-binding protein/CD14 expression in rats after thermal injury. Co-operation with the RanGTPase system allows them to bind and subsequently release their substrates on opposite sides of the nuclear envelope, which in turn ensures a directed nucleocytoplasmic transport.

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