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Adapalene is an expensive drug used to treat mild to moderate acne. This drug is slightly more popular than comparable drugs. It is available in generic and brand versions. Over-the-counter Adapalene is now available without a prescription.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Catapres, Atarax, Dilantin, Neurontin, Celebrex, Naprosyn, Theolair, Glucotrol, Reminyl, Pioplus, Diworm, Xeristar, Tarnasol, Fluxol, Odoman,


Adapalene is a third-generation topical retinoid primarily used in the treatment of acne. Adapalene is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adapalene gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adapalene works under the skin surface to unclog pores and clear up pimples. Adapalene is also known as Adapalene, Adapen, Adaferin. Generic name of Adapalene is Adapalene.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once.

Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel): For acne: Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well. Children—Use and dose must be determined by your doctor.


If you overdose Adapalene and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adapalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid exposure to sunlight or tanning beds. Adapalene can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid (common in topical acne medications or skin cleansers).

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

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Capsaicin-evoked mechanical allodynia and hyperalgesia cross-nerve territories. The calibration factor derived from the original method increased with the applied normal load, which indicates that separate calibration should be required for every given applied normal load to keep the accuracy of friction measurement. We have applied a recently developed method (Langmuir 2006, 22, 5509-5519) to determine charge numbers per adsorbed molecule and packing densities in self-assembled monolayers (SAMs) of octadecanethiol (C18SH), a representative long-chain thiol. Here we present this finding in a broader perspective and discuss the unique features of this gene which might explain its role as a general regulator of resistance responses against a class of pathogens that have previously not been associated to the classical resistance (R) gene type of defense. The value of screening for retinopathy and microalbuminuria in patients with type 2 diabetes in primary health care. The influence of rehabilitation on peak oxygen consumption in patients after myocardial infarction treated with beta-blockers. Three subjects had to discontinue disposable lens wear because of adverse reactions to trapped cellular debris and corneal microcysts. In multiple regression models, these associations, excluding TG/cholesterol ratio of LDL, remained significant and independent of possible confounders including age, sex, body mass index, insulin resistance index (HOMA-IR), and adiponectin, whereas the associations of ANGPTL3 with the lipoprotein parameters were less significant when apoC-II/C-III ratio was included in the models. Assessment of congitive functions in patients post acute lymphoblastic leukemia treatment used P300 event related potential. The greatest reduction in the three plant parts was shown in Wujing 15 compared with the other two varieties.

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Current strategies are frequently ineffective, in part because of a mismatch between the sudden onset and brief duration of breakthrough pain and the slower onset and more prolonged duration of oral immediate-release opioids. Human cytotoxic ticlopidine adverse drug reactions lymphocyte priming assays were done with dendritic cells loaded with Mel888 cells before the addition of reovirus. Perceptions of child sexual abuse as a public health problem--Vermont, September 1995. Based on the severity of the symptoms and signs, three degrees of hyperstimulation have been described: mild, moderate and severe. The high rate of dropout from treatment programs is one of the most serious problems in the field of drug dependence. The therapist must be sensitive to issues such as sensory loss, debilitating illnesses, and death when leading geriatric psychotherapy groups. The results were interpreted to suggest distinct developmental trends in set-switching and set-maintenance abilities required by the WCST. These later two emerging technologies need further exposure to better define their role in our clinical practice. Vascular compliance and vasoconstrictive reactions in rat hindlimbs: comparison between storage temperatures of -1 degree C and 4 degrees C.

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