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Admax (Calcitriol)
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Admax

Admax is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Admax is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Actical, Admax, Alfacalcirol, Alfarich, Apcical, Arachitol, Aristrol, Biocal, Biocitral, Bonestat, Bonetuf, Calasto, Calcibest, Calcigra, Calcikind, Calcirol, Calcit, Calcor, Caldikind, Calsure, Caltin, Carcal, Cholical, Citroj, Denscal, Dmcal, Estovon, Fovit, Koncal, Laretol, Nutribone, Osteobel, Ostriol, Riecal, Rockbon, Septriol, Solbiocal, Statbone, Vitalpha

Similar Products:
Imodium, Remeron, Nuvigil, Tricor, Flomax, Mircette, Evista, Teraxans, Azomax, Regtin, Urivate, Selamb,

Also known as: Calcitriol

Description

Generic Admax is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Admax are intestine and bone. Generic Admax receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Admax may also act on the kidney and the parathyroid glands. Generic Admax is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Admax has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Admax, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Admax in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Admax produces other independent beneficial effects. Admax is also known as Calcitriol. Generic Admax treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Admax is Calcitriol. Brand name of Generic Admax is Admax.

Dosage

Generic Admax is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Admax suddenly.

Overdose

If you overdose Generic Admax and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Admax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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However, cells with a mutant DNA2 allele lacking the corresponding N-terminal region were severely impaired in growth, being unable to grow at 37 degrees C, indicating that the N-terminal region contains a domain critical for a cellular function(s) of Dna2. The driving force is approximately proportional to the temperature gradient, but not sensitive to the system temperature. Cholesterol-sphingolipid microdomains (lipid rafts) are part of the machinery ensuring correct intracellular trafficking of proteins and lipids. In epidemiology, hypereosinophilia seems to reflect an inflammatory reaction in the airways, which may be linked to obstructive airflow limitation. By photographic evaluation, 12 of 17 patients (70.6 percent) were classified as having a normal head shape (grade 4) and five of 17 (29.4 percent) as having minor residual deformities (grade 3). A provocative test with SPECT with 99mTc-HmPAO to be done during the episode of orthostatic hypotension may contribute to clinical assessment of complex changes in cerebral regional perfusion. Once established, each physician-patient relationship faces termination. A complex composed of bovine collagen type I, extracted from tendons, and hydroxyapatite (HA), was evaluated in two sites: as onlay in the femur and on the periosteal surface of the calvarium of rats. With the relatively low diurnal variability, there does not appear to be a need to make sure serial measurements of Lp-PLA(2) mass and activity are taken at the same time of the day.

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Currently, there is no proven sensitive or specific method for predicting pathological fracture of the femur. The Center for Biostabilization at UC Davis is attempting to stabilize mammalian cells in the dry state. Dissecting the contributions of the different phosphorylated tyrosine motifs of the receptor to downstream signaling events in macrophages is not only important for our understanding of CSF-1R function, but also for the development of inhibitors to treat diseases where infiltrating macrophages contribute to their progression. There is a lack of evidence on the clinical efficacy and safety of the recently released Chinese botulinum toxin serotype A (Prosigne) for the treatment of focal dystonias and hemifacial spasm. Despite the high mortality, they should be aggressively treated because infection and acute respiratory failure are potentially reversible. Emergence of minute rhythms of small intestinal smooth muscle spike activity during adaptation. This work provides a rapid and effective technique for analyzing the species composition of Bacteroides in human gut. The methods used were paired comparison and direct ranking of nine stimuli.

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The thymus of 3- to 8-year-old cattle with clinical signs frequently had mild to advanced involution. A serious side effect was the initiation of osteolysis in the femora far from the implantation site causing extended defects in the cortical bone. RET oncogene amplification in thyroid cancer: correlations with radiation-associated and high-grade malignancy. Detection of atherosclerosis using a novel positron-sensitive probe and 18-fluorodeoxyglucose (FDG). They exhibited a functional hMR-mediated endocytic capacity of a soluble ligand but failed to ingest classical particulate ligands of MR such as zymosan, Mycobacterium kansasii, or trimannoside bovine serum albumin-coated latex beads. Such a slow mode was previously attributed to some large complexes or supramolecular structures formed between water and these small organic molecules. The IonPac AS14A is a recently developed stationary phase that was produced using a new block-grafting technique, which enables the preparation of high-water-content anion exchangers with excellent peak shape and good chromatographic efficiency. The aims of this study were to estimate the rate of hospital emergency services (HES) visits per health area, the associated percentage of admissions and the standardized HES utilization ratio, and to analyze their relationship with hospital resources. An alternative pathway for bile acid biosynthesis involving the peroxisomal L-bifunctional protein (LBP) has been proposed. Testicular protein Spag5 has similarity to mitotic spindle protein Deepest and binds outer dense fiber protein Odf1.

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Correlation between surface and bulk structures of alcohol-water mixtures. Compared to conventional pull-out suturing, several key modifications to surgical techniques were used. The organization of carbonic anhydrase (CA) system in halo- and alkaliphilic cyanobacterium Rhabdoderma lineare was studied by Western blot analysis and immunocytochemical electron microscopy. Compared with wild-type mice, these mice markedly accumulated plasma lipids and lipases. Little is known about neurogenic regulation of uterine contractility in mares. The reformed LLNA using auricle thickness and weighing as observed markers for irritation, and using lymph nodes weighing and proliferation of lymphocyte as observed markers for sensitization, could evaluate both sensitization and irritation at the same time.

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We found that caspase-14 cleaves the FLG repeat unit and identified two caspase-14 cleavage sites. The 15AB-binding proteins, candidates for the cellular recombinogenic protein, are now isolated and being characterized. We report that flagellin induces recruitment of two closely related U-box E3 ubiquitin ligases, PUB12 and PUB13, to FLS2 receptor complex in Arabidopsis. Renal cell carcinoma metastases to the thyroid gland-8 cases reported. The results suggest that the peripheral 5-HT pathway is a potential therapeutic target of the treatment for premature ejaculation. However, further studies exploring antibiotic concentrations in tissues are warranted. CMS plans changes in guidelines for consent, alcohol-based preps. New gatekeepers of reproduction: GPR54 and its cognate ligand, KiSS-1. The polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic aromatic hydrocarbons (NPAHs) of each fraction were determined by high-performance liquid chromatography (HPLC). However, poor long-term survival and insufficiently reproducible differentiation to functionally appropriate cells in vivo still present major obstacles for translation of this methodology to clinical applications.

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Recursive partitioning analysis more accurately identifies nodal disease and metastatic disease as the most important prognostic variables. Twice sealed-rupture of a small abdominal aortic aneurysm with unusual computed tomography findings. Alterations in pulse wave velocity and augmentation index in Australian aboriginals: characteristics and mechanisms. Emergency department crowding: time for interventions and policy evaluations. To approach this question, a technique is required that can monitor spatially-resolved changes in cortical stiffness with good time resolution. A left ventricular cineangiogram showed the communication between the left ventricle and the right ventricle through a false aneurysm. We report the case of a 35-year-old woman with chronic active Epstein-Barr virus (EBV) infection (CAEBV). It is an important molecular mechanism of tumor metastasis that over-expression of CD151 promotes migration of tumor cells.

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MRI is particularly useful in planning the management of those conditions where surgical or medical intervention can result in improvement or resolution of symptoms. Total parathyroidectomy with autotransplantation into the sternocleidomastoid muscle. When accidental exposure to ionizing radiations is suspected, optimal choice of a treatment strategy requires, in addition to information about the clinical signs and physical dosimetry, a determination by biological parameters of the dose received. This mechanism could explain the diffuse migratory behavior of high-grade glioma cancer cells within the brain. In the surgical treatment of severe osteoarthritis, TKA shows a highly increasing number, whereas HTO is decreasing. Myosin-1a is critical for normal brush border structure and composition. We have found that it is feasible to record from dozens of single units in the motor cortex for extended periods of time and that these signals can be decoded in a closedloop, real-time system to generate goal-directed behavior of external devices. This explanation is in accord with the previous work on the photochemical reaction and with the effect of temperature on the latent period.

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Antitumor Effect of Immunizations With Fusions of Dendritic and Glioma Cells in a Mouse Brain Tumor Model. Alteration of biological characteristics of HSCs with the anti-TGF-beta1 miRNAs was preliminarily evaluated by measuring the expression levels of TGF-beta1 and its downstream molecules, including collagen I, matrix metalloproteinase 2 (MMP2), tissue inhibitor of metalloproteinase 1 (TIMP-1), etc. To compensate for these effects, we present two parameters defined as the ratio of the harmonic to the fundamental component (HFR) and the ratio of the harmonic to squared fundamental (HSFR). Stable transduction of myogenic cells with lentiviral vectors expressing a minidystrophin. A summary of the functional analysis of this EST collection is presented, and genes of particular interest are highlighted. Newcastle disease viruses isolated from Hong Kong live bird markets (LBMs) were not detected by a USDA-validated matrix gene real-time reverse transcription-PCR (RT-PCR) assay. We have also shown here that transcriptional activation by artificial recruitment of the TATA-binding protein (TBP) to the promoter is also defective in the absence of RPB4. In conclusion, poor coupling in the sinus node seems to be sufficient to produce most arrhythmias in the sick sinus syndrome. The observed improvement of HRV seems to be facilitated by weight loss.

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Fluorescence microscopic studies indicated that tumor localization of verteporfin changed from predominantly within the tumor vasculature at 15 min after injection, to being throughout the tumor parenchyma at 3 h after injection. This field is not homogenous and encompasses a variety of technologies, which are in various stages of development. Peer-assisted learning in teaching clinical examination to junior medical students. Basal insulin: physiology, pharmacology, and clinical implications. GLP-1 agonists and the DPP-IV inhibitors exploit the innate incretin system to improve glycemia while promoting satiety and weight management. The findings demonstrate a consistent pattern of health risk behaviors and adverse biological outcomes associated with less perceived parental monitoring.

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To clarify whether SH-group-containing molecules can prevent CAA-induced cell death, we studied the effect of mesna and cysteine on necrosis, apoptosis, and protein content in a human proximal tubule-derived cell line (IHKE cells) treated with CAA. Ivermectin treatment of a traveler who returned from Peru with cutaneous gnathostomiasis. Selective serotonin reuptake inhibitors, especially Sertraline and Citalopram, with a very gradual dose titration are likely to benefit. The forested hilly and foothill regions of north-east India are highly endemic for malaria and have a distinct epidemiological pattern. Th1-type cytokines are expressed predominantly in primary hepatic cancer and the adjacent liver tissue. As part of the mobic 15 mg dosage Balanced Budget Act of 1997, Congress created the Medicare Rural Hospital Flexibility Program for limited-service hospitals. They are formed in the bone marrow and mature cells are stimulated by PTH and locally acting agents such as transforming growth factor alpha (TGFalpha), tumor necrosis factor (TNF) interleukin 1 (IL-1) and interleukin 6 (IL-6). The ADP-ribosylation enzyme activity of PTx is thought to be the major factor responsible for the histamine-sensitising activity detected in vivo. Outcome in meningococcemia: a relationship between quantity and quality?.

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Identification and functional screening of microRNAs highly deregulated in colorectal cancer. It has been shown that supplementation of media with 100 microM Mn(II) considerably enhanced the resistance of this bacterium to oxidative killing by superoxide. The computed tomography of the brain showed aneurismal arteriopathy of the circle of Willis. In addition, loculated pericardial effusions, with or without associated tamponade, have to be considered in the differential diagnosis. Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain. Early-age heat exposure affects skeletal muscle satellite cell proliferation and differentiation in chicks. DBF and DOS files are used by a Clipper 5.2d compiled program to handle demographic data, clinical reports (32,000/year) and diagnostic codes of more than 52,000 patients. This study has assessed the magnitude and nature of the problem and reviewed the legislation, current practices, and institutional capacities for preventing drinking and driving. These flomax dosing bid models progress in size and complexity as we move from small to medium to large tribes.

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To explore the functions of the two different protein structures, the synaptonemal complex and the cohesin complex, in mammalian male meiotic cells, we have analyzed how absence of the axial element affects early meiotic chromosome behavior. The sympathetic nervous system is thought to play a role in the genesis of ventricular tachyarrhythmias (VT). In this study, the influence of rh-Cu/Zn-SOD application to thermally injured tissue of rabbit backskin was examined. Multipolypeptide IFT particles, composed of complexes A and B, carry flagellar precursors to their assembly site at the flagellar tip (anterograde) cardizem medication template powered by kinesin, and turnover products from the tip back to the cytoplasm (retrograde) driven by cytoplasmic dynein. These data also suggest that varying moisture regimes result in different effects of soil NO(3)(-)-N leaching on residual whole soil delta(15)N. The aim of this research was to investigate the epidemiology of tobacco smoking among a previously understudied group of rural Japanese nurses. Cardiac injuries caused by blunt trauma: an autopsy based assessment of the injury pattern. Deletion studies with the promoter demonstrated a critical region between -1057 and -981 bp of the promoter that is responsive to MMS treatment.

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Seedling botanical characters and determination of effective components on Dioscorea zingerbrensis by space mutation. Why do obese patients not lose more weight when treated with low-calorie diets?. Mortality from natural causes is markedly increased in schizophrenia, and the role of polypharmacy remains controversial. Future studies should assess the effect of exercise programs and revascularization on cadence and step length in PAD. In a patient with two different causes of abnormal thyroid function, it is important to seek an encompassing clinical scenario. Estrogens are reported to cause hypolipidemia in mammalians inducing hepatic LDL receptor. This strategy carries obvious benefits, but may also result in severe consequences for older larvae that run low on energy.

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The impact of ethnicity on the presentation of polycystic ovarian syndrome. Behavioral testing during adulthood assessed pain thresholds using hot-plate (HP) and tail-flick (TF) tests, alcohol moduretic preference, and locomotor activity (baseline and postamphetamine). The action potential durations of the Purkinje fiber and free wall of the right ventricle were longer in the chronic atrioventricular block dogs than in the dogs with normal sinus rhythm. The aim of this study was to establish a practical method of monitoring the renal excretion of water and solutes over a complete 24 h cycle. A simulation study shows that denoising data prior to testing can achieve greater power in detecting the aberrant spot than using the raw data without denoising. Moreover, polymerase chain reactions using GDI and GD2 revealed only glycerol dehydratase genes of positive L.

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We conclude that variations provided and selected by the terms of the three-term contingency are powerful means for understanding novel behavior. Spectra MRSA, a new chromogenic agar medium to screen for methicillin-resistant Staphylococcus aureus. Production of aminopeptidase Y is not markedly affected by nitrogen regulation. An 86-year-old woman presented to the Emergency Department with acute onset of abdominal pain occurring following a bowel movement. Low-dose peanut exposure during pregnancy and lactation reduced this risk. A review of the barium study of 507 children for the presence and severity of gastroesophageal reflux revealed 79 cases with coexisting pulmonary disease.

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To clarify the biological and clinical profiles of tumors with genetic abnormalities of the short arm of chromosome 1, we performed deletion mapping on 1p on 92 neuroblastoma tissues and corresponding noncancerous samples obtained from 92 cases for 24 micro- or minisatellite loci. In territorial contests, not only acoustic or other signals, but also the movements of a territorial intruder are likely to influence the response of a resident. Intervention is recommended in cases where there is increased risk of mortality, as in severe obstruction of the tracheobronchial tree. The meeting provides investigators from different world areas a forum and an opportunity for discussion. The aim of the thermoradiotherapy was to reduce the substantial risk of symptomatic chest wall disease.

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These results indicate that certain breeds are predisposed to the development of elevated cutaneous M pachydermatis populations and that concurrent skin diseases can frequently be identified in affected dogs. Quantitative assessment of oxyphilic cell lesions of the thyroid gland prevacid side effects reviews on fine needle aspiration samples. As a first step in evaluating the genetics of pigment pattern diversification in the group, we then examine the phenotypes of interspecific hybrids. A 293T cell line with UBE2C stable expression is successfully established and UBE2C promoted the proliferation of 293T cells. MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951. Analysis of haemochromatosis gene mutations in a population from the Mediterranean Basin. Ten months following total urethrectomy, multiple pulmonary metastases had developed. These assumptions were met, leading us to conclude that peripheral OT and AVP are measurable via urinary assay and that such an assay is a valid means of evaluating social condition in this species. In all femoral shaft fractures, scrutiny of the femoral neck is mandatory in order to direct proper management toward this potentially devastating complication. Results show that the number of lanes at the four-legged signalized intersections significantly increases motorcycle crashes largely because of the higher exposure resulting from higher motorcycle accumulation at the stop line.

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In the second experiment, VBEs were found not to correlate with the size of the horizontal-vertical illusion (HVI). This enhanced neural response to irrelevant visual stimuli under auditory load suggests that exhausting capacity within one modality selectively compromises inhibitory processes required for filtering stimuli in another. Perimenstrual catamenial epilepsy may in part be due to withdrawal of the endogenous progesterone-derived neurosteroid allopregnanolone that potentiates gamma-aminobutyric acidA (GABA(A)) receptor-mediated inhibition. Recently, particularly after the completion of the Human Genome Project, proteomics (systematic analysis of proteins for their identity, quantity and function) has been recognized as an emerging subdiscipline of modern sciences. An in vivo cinefluoroscopic study of subjects without cervical abnormality. Disopyramide: a new agent for effective therapy of ventricular dysrhythmias. Double-bundle reconstruction of the ACL did not improve function or stability compared with single-bundle reconstruction. Hypertension is associated with the probability of CKD with eGFR less than 60 ml/min/1.73 m(2). To validate a computerized expert system evaluating visual fields in a prospective clinical trial, the Ischemic Optic Neuropathy Decompression Trial (IONDT).

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A thickened cytoplasm, a nuclear pleomorphism, a thickened nuclear rim, a coarse chromatin, an uneven chromatin distribution, and an OG-philic cytoplasm were frequently observed in the carcinomas in situ and severe dysplasias compared with the moderate dysplasias. The effects of folate deficiency include hyperhomocysteinemia, megaloblastic anemia, and mood disorders. This may explain why recent experiments did not find weak localization in graphene. The target of the RA therapy should be focused on this destructive aspect in relation to the original RA pathophysiology. Foods formulation for people with celiac disease based on quinoa (Chenopoduim quinoa), cereal flours and starches mixtures. What makes the bacteriophage lambda Red system useful for genetic engineering: molecular mechanism and biological function. In procedures that involve multiple needle insertions such as transrectal ultrasound guided prostate brachytherapy, it is important to reduce tissue deformation before puncture and during insertion.

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By using GLC with a flame-ionization detector, linear concentration-response curves were obtained in the 1-6 microgram/ml range. Classic mastoid surgical procedures were performed in the Anatomy Department: exposing sigmoid sinus, facial nerve, labyrinth, dura mater, jugular bulb, and internal carotid artery. No evidence is found for additional motions characterized by 90 degrees flips recently deduced from QENS data alone. The method described here, which we called integral hot staining (IHS), represents a very simple, reproducible, and conservative assay for multiparameter DNA analysis using a bench-top flow cytometer. DNA microarray technology offers the advantage of analyzing thousands of genes simultaneously, with the potential to determine healthy phenotypic changes in gene expression. Taken together, the data suggests that HIV-1 infected individuals with hyperglycemia could potentially be at a higher risk of developing CNS related complications. The bile duct carcinomas of PBM were exclusively identified by the type of cystic dilation. Comparative efficacy of various toxoids against salmonellosis in poultry. Many societal factors threaten to compromise realisation of the public health gains that immunisation can achieve in the next decade and beyond--understanding these factors is imperative.

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