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Agoxin (Digoxin)

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Agoxin is used to treat heart failure, usually along with other medications. It is also used to treat a certain type of irregular heartbeat (chronic atrial fibrillation). Treating heart failure may help maintain your ability to walk and exercise and may improve the strength of your heart. Treating an irregular heartbeat can decrease the risk for blood clots, an effect that may reduce your risk for a heart attack or stroke.

Other names for this medication:
Agoxin, Cardiacin, Cardiogoxin, Digacin, Digibind, Digitek, Digobal, Digohan, Digoregen, Digosin, Digossina, Digoxen, Digoxin, Digoxine, Digoxinum, Eudigox, Fargoxin, Halfdigoxin, Lanadicor, Lanibos, Lanicor, Lenoxin, Purgoxin, Sigmaxin, Vidaxil

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Cipro, Nolvadex, Floxin, Loxitane, Pamelor, Reminyl, Microzide, Hydrea, Neoral, Sumycin, Reloxyl, Glimet, Theophylline, Klazidem, Tavist, Lotensyl, Cefix,

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Also known as: Digoxin


Digoxin injection is given in combination with a diuretic (water pill) and an angiotensin-converting enzyme (ACE) inhibitor to treat heart failure in adults and children. It is also used to treat adults with atrial fibrillation (a heart rhythm problem).

Digoxin belongs to the class of medicines called cardiac glycosides. It is used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of the hands and ankles in patients with heart problems.

This medicine is to be given only by or under the direct supervision of a doctor.


This section provides information on the proper use of a number of products that contain digoxin. It may not be specific to Agoxin Pediatric. Please read with care.

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is usually given as a shot into a muscle or into a vein.

Your doctor may give you a few doses of this medicine until your condition improves, and then you may be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Agoxin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of digoxin can be fatal.

Overdose symptoms may include nausea, vomiting, loss of appetite, and feeling tired.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Agoxin dosage information

Side effects

The most common side effects associated with Agoxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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We have compared this complex with the catalytic domains of diphtheria toxin, heat labile enterotoxin, and pertussis toxin, all three of which it closely resembles. Interaction between the heme oxygenase system and aldosterone in hypertension. In general down-regulation of cdc25C transcription by reducing the levels of active cdc2 kinase contributes to G(2) arrest and G(2)/M checkpoint control. Mitochondrial disorders recognized in the neonatal period usually present as a metabolic crisis combined with one or several organ manifestations. While most gene silencing studies have been performed on annuals, little is known about the expression of key components of this process (like ARGONAUTE proteins) in ornamentals. Experiment shows that PM reacted with TCQ in methanol with light and the complex was formed. Towards a quantitative understanding of the epidemiology of Keystone virus in the eastern United States. We demonstrate a data storage density of 1 Tb in(-2), which is limited only by the size of the tip. This is the largest single-center series of subjects with SMS that includes ophthalmic evaluation.

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In the human testis, the antibody specifically recognized Apg-1, which was absent in the testis without germ cells (Sertoli-cell-only syndrome) or arrested at spermatogonia. The schizophrenia group did not exhibit any resting-state correlation or anticorrelation between the MPFC and the VLPFC or insula. Both HDM2 and HDMX bind to p53 and prevent cell cycle arrest or apoptosis in damaged cells. To examine the association of A1C levels and fasting plasma glucose (FPG) with diabetic retinopathy in the U.S. The data are reproduced well by a computer simulation of a random walk model based on diffusion of molecules within such a structure, allowing determination of the surface film thickness.

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Body surface countings showed that a significant increase in the count rate over the spleen occurred concomitantly with the decrease in the circulating platelet-bound radioactivity (PBR). Rust infection resulted in increased accumulation of isoflavonoids and flavonoids in leaves of all soybean genotypes tested. Phosphorylation in vivo of proteins associated with heterogenous nuclear RNA in HeLa cell nuclei. We concluded that ABR are an unrecognized component of undamaged root systems. Eighty percent of foreign bodies were polyethylene central venous pressure catheters, cut in two by the needle introducer. Chondrocytes isolated from human knee articular cartilage were cultured in a three-dimensional alginate culture system. Value of isotope study with ytterbium-169 citrate in the diagnosis of pulmonary opacities of cancerous nature. To determine the prevalence of reagent serology for suspected acute toxoplasmosis in pregnant women and to describe clinical, laboratory and therapeutic profiles of mothers and their children. These results suggested that PRIP directly interacts with the catalytic subunits of two distinct phosphatases in a mutually exclusive manner and the interactions are regulated by phosphorylation, thus functioning as a scaffold to regulate the activities and subcellular localizations of both PP1 and PP2A in phospho-dependent cellular signaling.

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The substrate stimulation of renal secretory transport of cardiotrast and penicillin have been studied in conscious rats. Reduced glutathione system: role in cancer development, prevention and treatment (review). In this paper, a Medical Diagnosis Decision System (MDDSS) based on SVM has been established to intellectively diagnose 4 types of acid-base disturbance. Recent developments in related technologies are also included from review papers. Doses of 25(OH)D3 were 20, 100, 500, or 1000 microgram/day given orally for 7--10 days. The monotremes therefore provide insight into the ancestral drivers for lactation and how these have adapted in different lineages.

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Rates of acquisition in single (mand-only and tact-only) versus mixed (mand-tact) presentation were comparable, in contrast to earlier investigations. Protein and creatinine excretion rates were measured in the same specimens. Neurofibromatosis, gigantism, elephantiasis neuromatosa and recurrent massive subperiosteal hematoma: a new case report and review of 7 case reports from the literature. Blocking MSC-induced transduction of the PI3K-Akt-Bad pathway may be a potential strategy for a targeted therapy to combat leukemia. Also, more TUNEL-positive profiles were detected in the subventricular zone, following mutant alpha-synuclein expression and in the olfactory bulb, following wild-type and mutant alpha-synuclein expression. In addition we found that both the parental Salmonella and its alcohol using adhI mutant expressed substantial levels of a dye-linked aldehyde dehydrogenase that is presumably responsible for conversion of acetaldehyde to acetate. Apoptosis in the jejunal mucosa was suppressed in rats with ventromedial hypothalamus lesions. Potential utility of PPARalpha activation in the prevention of ischemic and drug-induced acute renal damage. Auditory nerve input is not an absolute requirement for the expression, distribution and calcium permeability of AMPA receptors in the adult rat ventral cochlear nucleus.

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We evaluated the original PIOPED database to obtain the consensus probability estimates of pulmonary embolism (PE) among patients stratified according to the presence or absence of prior CPD. Although radiosurgery tends to cause seizures temporarily, the radiosurgery may improve seizure outcomes in patients with AVM-related seizures, especially in patients with AVM obliteration. However, the relative contribution of each receptor to endothelial functions critical to angiogenesis and their roles in vivo have not been established. In group I, the teeth were instrumented and irrigated by conventional irrigation using 27-gauge irrigation needle. Likewise, delayed or overlooked referral of patients harboring malignant tumors is strongly associated with diminished outcomes. Scientific basis for exercise program recommended to women in various ages. The aim of the study was to investigate the effects of hormone replacement therapy (HRT) on myocardial repolarization characteristics in postmenopausal women without coronary artery disease. Compared with conventional RP-materials on-line coupling of sol-gel-generated silica matrices with a pore structure designed to retain antibodies poses additional problems caused by their lower pressure tolerance and by the necessity to match the mobile phases not only to take into account the chromatographic properties but also the conformational stability of the antibodies.

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The systolic and diastolic arterial blood pressures and heart rate increased within 2 minutes of buccal exposure to either the intact or the damaged ProStep nicotine product. The resin-only cartridge was tested in at 6 centers throughout Italy and included patients that had experienced previous reactions to the carbon-resin cartridge. Bacterial vaginosis (BV) - a syndrome characterised by a shift in vaginal flora - appears to be particularly common in sub-Saharan Africa, but little is known of the pattern of vaginal flora associated with BV in Africa. Sequence diversity of the OprD protein of environmental Pseudomonas strains. This concern has led to intense clinical and basic research aimed at determining the incidence and causes of wound recurrence and developing preventative measures to address this problem. The objective of this study was to describe the frequency, type and predictors of errors in medication history, and to evaluate the extent to which standard care corrects these errors. From our experimental data it can be seen out that one of the geochemical parameters, Total Alkali (TA), may be an appropriate index to select materials of low radiological risk. In these animals, the locomotor effects of amphetamine and caffeine, two psychostimulant drugs that affect dopamine and adenosine signaling, respectively, were markedly reduced. Furthermore, the support vector machine is used for classification of the mental tasks.

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We performed tumor resection successfully, and she had no symptoms of coagulopathy thereafter. The presence of symmetry breaking terms in the local shear can produce localized ballooning instabilities in regions of small average magnetic shear which lower first-ballooning stability thresholds and can potentially eliminate the second stability regime. Urate by comparison has a specific inhibitor activity of 45 anti-Units per mg using human MM creatine kinase. It is hoped that a more structured approach to model validation can help to improve the credibility of musculoskeletal models. Genes encoding sarcomeric proteins specific for fast or slow fibres are frequently used as lineage markers. Formation and function of the myofibroblast during tissue repair. Infrared spectrum of the hyponitrite dianion, N(2)O(2)2-, isolated and insulated from stabilizing metal cations in solid argon.

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There is only a decrease of the mortality rate during hospitalisation. Dermal exposure assessment needs to be performed in future studies among these workers. On the other hand, there is evidence that body mass index (BMI), an estimate of overall obesity, fulfills this function as effectively as does WC. Mouse cells are non-permissive to human immunodeficiency virus type 1 (HIV) in that there is a pronounced post-integration block to viral replication. However, the therapeutic benefit of anticoagulation has not yet been demonstrated experimentally or clinically. Social interaction in pain: reinforcing pain behaviors or building intimacy?. Thermal esophageal lesions after radiofrequency catheter ablation of left atrial arrhythmias. Surgical angioplasty of the left main coronary artery: follow-up with magnetic resonance imaging.

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No evidence of a detrimental effect of fish intake in this population was observed. Although the yeast fbh1 mutant shows an increase in sensitivity to DNA damaging agents, FBH1(-)(/)(-) DT40 clones show no prominent sensitivity, suggesting that the loss of FBH1 might be compensated by other genes. Long-lived plasma cells can survive for a lifespan within a complex niche in the bone marrow and provide continuous protective serum antibody levels. We reviewed the medical literature to identify features desired by different users and associated with guideline use to develop a framework of implementability and found that most guidelines do not contain these elements. injection of CdCl2 (1 mg Cd/kg body wt), 2 h prior to irradiation resulted in increasing of DNA lesions in peripheral blood lymphocytes(PBL) when compared to non-injected animals. Design of a vector magnet for the measurements of anisotropic magnetoresistance and rotational magneto-optic Kerr effect. On the development of the cerebellum of the trout, Salmo gairdneri. Multiphoton in situ detection of a potentially valuable label for biological applications. 1 in 1000) and in comparing odds ratios from different hazards, we examined the use of time intervals between expected harmful events to communicate risk. Surprisingly, a double tyrosine to alanine mutant of Siglec-5 could still mediate strong inhibition of serotonin release in the absence of detectable tyrosine phosphorylation, whereas a double tyrosine to phenylalanine mutant lost all inhibitory activity.

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The first one is a conventional picture of interacting micelles where a reduction in the molecular surface area, leading to an increase of the aggregate dimension, is paid to reduce intermicellar interactions: it foresees a monotonous increase of the aggregation number with concentration. The ustA mutant grew slower than the wild-type parent strain in rich medium, resulting in a lower yield in stationary phase. This review highlights the many roles mass spectrometry plays in the discovery and development of new therapeutics by both the pharmaceutical and the biotechnology industries. The body was severely burned and was not formally identified as the owner of the house. Studies of the familial aggregation of chronic bronchitis and obstructive airways disease. Complications after emergency repair of an incarcerated hernia repair are higher than those associated with elective surgery because of congestion of the sac. Confirmatory factor analyses indicated that a single factor model with one pair of correlated errors fit the data well. The coating polymer was the most important factor determining the delay in the onset of crystallization, with the more hydrophilic polymer, hypromellose, having a higher solubilization potential for the guaifenesin and delaying crystallization for longer period (3 or 6 months in tablets stored at 40 degrees C or 25 degrees C, respectively) than the more hydrophobic ethylcellulose, which displayed a lower solubilization potential for guaifenesin (crystal growth on tablets cured for 2 hours at 60 degrees C occurred within 3 weeks, whereas uncoated tablets displayed surface crystal growth after 30 minutes).

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The aim of this study was to clinically evaluate immediate functionally loaded (IFL) and immediate nonfunctionally loaded (INFL) implants for various indications compared to a control group with a conventional healing period. Adjunct treatments such as exercise may become increasingly important and helpful in the changing health care delivery and reimbursement environment where more short-term and self-help therapies are being strongly encouraged. Previously, we showed that a 60-bp subgenomic HBV DNA (15AB, nt 1555-1914 of HBV DNA) is a hot spot for the genomic recombination, and the cellular protein binding to 15AB may be the putative recombinogenic protein. Late in the reaction there may be a few epithelioid cells and foreign body giant cells. Our result suggests that infection occurs sporadically by person-to-person transmission what is a strong dose of ativan route but further investigations are needed to determine the natural reservoir of infection. The Cancer Register encompasses more than 1800 women with a diagnosis of PA 1960 until 1992. Encapsulation of autologous adult cartilage cells (chondrocytes) in hydrolytically degradable hydrogels may provide a clinically viable tissue engineering therapy for replacement of damaged or osteoarthritic cartilage. Subjects were decidedly in favor of having the option to access results immediately via an online system, proposing some potential problems and potentially multiple benefits of such a system. Upon hormone binding, the GR translocates into the nucleus, where the hormone-activated GR-complex regulates the transcription of GR-responsive genes. Hexamethonium (30 mg/kg iv) inhibited RSNA, and tempol did not decrease RSNA after hexamethonium.

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Maxillary reconstruction using a multi fenofibrate tablets ip 145 mg uses in hindi -element free fibula flap based on a three-dimensional polyacrylic resin model. We propose preliminary guidelines for this syndrome in juvenile SLE to facilitate timely diagnosis and correct classification of patients. No sequence alteration was identified in the coding region of GCH1 in an affected individual. Adaptation and steady-state firing in motoneurones are assumed to be governed by summation of AHP conductance. Very little is known about this group with regard to their mental health status and the way they cope with their childhood memories. The proportion of visits to physicians other than dermatologists increased 2.1-fold from 1980 and 1981 to 1989 through 1991. AM enhanced the therapeutic potency of MSCs, including neurological improvement, possibly through inhibition of MSC apoptosis and induction of angiogenesis. In this prospective study the association between Helicobacter pylori infection and increased risk of myocardial infarction and stroke was substantially confounded by the relation between this infection, adult social class, and major cardiovascular risk factors.

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(2) Remarkable antidepressive response was obtained with Org GB94 in moderate and mild forms of endogenous, involutional and senile depression. The Website returns ranked lists of likely superfamilies and hence implicit structural predictions according to three computational techniques: BLAST, HMMER and a discriminative classifier SVM-BLOCKS. Low intake and low serum levels of vitamin D each appear to be associated with an increased risk for progression of osteoarthritis of the knee. Gene expression profiling during gland morphogenesis of a mutant and a glandless upland cotton. They differed from the usual features of nocturnal bruxism in hypoperfusion of the left frontal lobe, a poor response to l-dopa or bromocriptine therapy and a favourable response to metoclopramide. Important policy updates to the Medicare prescription drug benefit in 2007 include the subject areas of: (1) beneficiary enrollment, (2) transition medication fills, (3) standard benefit, (4) cost sharing, particularly for those who qualify for LIS, (5) enhancement of the Medicare Prescription Drug Plan Finder, (6) beneficiary complaints, (7) discontinuation of coverage for erectile dysfunction drugs, (8) vaccine coverage by the Medicare prescription drug benefit, (9) syringes in long-term care, (10) donation of unused medications by beneficiaries, (11) implementation of the NPI, and (12) preventive services covered by the Medicare program. Fas is a widely expressed cell surface protein that transduces an apoptotic signal after interaction with its natural ligand FasL. Successful treatment of calcific uremic arteriolopathy in a pediatric dialysis patient.

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The survival of motor neurons protein (SMN), the product of the neurodegenerative disease spinal muscular atrophy (SMA) gene, functions as an assembly factor for snRNPs and likely other RNPs. The construction is applicable to finite-dimensional systems, and we explicitly show that for simple mean-field glass models it recovers, justifies, and generalizes the known results. Cardiac troponin I concentrations were measured in serial venous blood samples drawn just before cardiopulmonary bypass and after aortic unclamping at 6, 9, 12, and 24 hours and daily thereafter for 5 days. In Saccharomyces cerevisiae, Snf1 protein kinase is important for growth on carbon sources that are less preferred than glucose. These results suggest that prolonged activation of the P2 receptors inhibits AVP-stimulated fluid transport and cAMP responses in AQP2 transfected MDCK cells.

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MEDCHI, the Maryland State Medical Society 2011 legislative and regulatory agenda. Dependence on control parameters such as peak nonlinear phase shift and cavity-length mismatch cozaar max dose are discussed. Limitations of cohort and case-control studies include misclassification, selection bias, and confounding. Regions of interest were the common carotid artery, the plaque, the internal carotid artery, and the external carotid artery to evaluate changes in each intensity value. From these findings, the patient was diagnosed with tumor of renal pelvis and ureter, and left total nephroureterectomy was performed. Statistical-mechanical theory of ultrasonic absorption in molecular liquids. An incisional biopsy specimen showed changes consistent with a diagnosis of inflammatory morphea. Two monoclonal antibodies (1A5 and 2C5) targeting at the RBD of S protein were isolated from mice immunized with inactivated SARS-CoV. The complicated floral structures that occur in Roridula most likely evolved as adaptations for bee pollination.

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The aim of this retrospective study was to evaluate the usefulness of MR imaging in excluding or confirming prilosec omeprazole 40 mg the diagnosis of diaphragmatic injury after blunt trauma. The p16(INK4) protein has been identified as a potent inhibitor of cyclin-dependent kinase (cdk)4 by blocking cdk4-mediated phosphorylation of the tumor suppressor retinoblastoma (Rb) protein, thus allowing Rb-mediated growth suppression. GROWTH AND SENESCENCE AS MEASURED BY THE RISE AND FALL OF MILK SECRETION WITH AGE. Flow cytometry analysis showed that the transduced cells cultured at 34.5 degrees C, like the parental cells at 37 degrees C, were smaller and less granular than the transduced cells incubated at 39 degrees C. The influence of propofol on the pharmacokinetics of alfentanil is poorly understood. With the devices, the light field as well as the radiation field, projected from the individual beam at any treatment position (i.e. Plasmonic lens made of multiple concentric metallic rings under radially polarized illumination.

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Chronic rhinosinusitis (CRS) is one of the most common inflammatory diseases with multiple etiologies. This article will summarise the reports on the biotechnological applications of bacterial tyrosinases as well as the current information available on the different types of this enzyme. Preliminary evaluation of anticonvulsant activity and neurotoxicity of some 1,4-substituted piperazine derivatives. Vitamin D metabolism within bone cells: effects on bone structure and strength. Here, we describe a series of phenotypic selection experiments, which resulted in the expression of different PfEMP1 and the detection of multiple full-length var gene transcripts in the mature trophozoite stage. By contrast, treprostinil had high affinity for the DP1, EP2 and IP receptors (Ki 4.4, 3.6 and 32 nM, respectively), low affinity for EP1 and EP4 receptors and even lower affinity for EP3, FP and TP receptors.

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Here, we demonstrate that scalloping is principally due to the noise reduction filtering that occurs when image samples are interpolated. Further work is required to determine the antigens recognized by many of the other mAb. This paper investigates a neural network model of the interaction between mood and memory. The clinical pattern of acquired resistance in many circumstances represents outgrowth of resistant clones that might have originally been present in the primary cancer at low frequency but that have expanded under the selective pressure imposed by targeted therapies. People with more severe mental retardation are vulnerable to leading lives characterized by underoccupation and lack of community involvement. However, in contrast to animal cells, ph(Thr11)H3 was distributed along the entire length of condensed chromosomes, whereas H3 phosphorylated at Ser10 and Ser28 appeared to be restricted to centromeric/pericentromeric chromatin.

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