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Alfatrim (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Astrim, Bacin, Bactelan, Bacticel, Bactipront, Bactramin, Bactricid, Cotreich, Cotribene, Cotrimox, Cotrimstada, Dhatrin, Doctrim, Editrim, Eliprim, Epitrim, Groprim, Kanprim, Medibiot, Metoxiprim, Neotrim, Netocur, Noxaprim, Nufaprim, Pehatrim, Septra, Septran, Servitrim, Sulfoid, Sulotrim, Suprimass, Tagremin, Terbosulfa, Trimethazol, Trimoks, Tripur, Urobactrim, Vanadyl, Wiatrim

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Also known as: Trimethoprim


Alfatrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Alfatrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Alfatrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Shake this medication well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Dosage is based on your medical condition and response to treatment.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping it too early may allow bacteria to continue to grow, which may result in a relapse of the infection.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Alfatrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Alfatrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Alfatrim is contraindicated in pediatric patients less than 2 months of age. Alfatrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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Finding NEMO: nestedness engendered by mutualistic organization in anemonefish and their hosts. All isoforms of the enzyme were found to be randomly distributed within all layers of the pellicle. A three year follow up study of the dental health of 12- and 15-year-old schoolchildren in Glasgow. In vitro study of the cytotoxic activity of sipunculid leukocytes towards allogeneic and xenogenic erythrocytes. The aim of this study was to investigate the effect of bisaramil--an antiarrhythmic drug under clinical trials-on free radical generation of isolated polymorph neutrophil granulocytes (PMN) and furthermore to compare its activity to that of well-known antiarrhythmics which have different modes of action. The occurrence of protein-bound mixed disulfides in rat tissues. Combination immunomodulator and antibiotic treatment in patients with inflammatory bowel disease and clostridium difficile infection. Combined evaluation of bedside clinical variables and the electrocardiogram for the differential diagnosis of paroxysmal atrioventricular reciprocating tachycardias in patients without pre-excitation. Four hundred nineteen patients who died in one of three academic, tertiary care ICUs over a 1-yr period.

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In fetal and paediatric normal thymus, EGF-receptor was expressed by subcapsular, cortical and medullary epithelial cells, whereas immunoreactivity for NGF-receptor was detected on only subcapsular and medullary epithelial cells. We investigated the profile of miRNA expression following IR in the human lung carcinoma cell line A549, and the expression profiles of IR-responsive miRNAs were confirmed by qRT-PCR. Cerebral toxicity of penicillins in relation to their hydrophobic character. The results were discussed in terms of their implications for clinicians. In this paper the haemocoagulative effect of the Vasolamin preparation was examined after intravenous application in cattle, sheep, and horses by means of tests.

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Generation of an infectious cDNA of a highly cardiovirulent coxsackievirus B3(CVB3m) and comparison to other infectious CVB3 cDNAs. Substantial correlations were seen among levels of cannabis, nicotine, and alcohol use and specifically between caffeine and nicotine. A 42-year-old Chinese man presented with the complaints of weakness of the lower extremities and urinary retention. The calculation scheme presents a strategy for calculating toric lenses and residual refractions based on a thin lens model of the spectacle correction, the cornea and the lens implant. The expected flood of Drosophila population genomics is expected to rapidly advance understanding of the dynamics of TEs. This paper reviews results from published, in press, and conference proceedings from 2007 and 2008 that link in-utero tobacco exposure to neurodevelopmental outcomes in exposed offspring. The clinical characteristics and CT imaging of these two groups were compared.

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botanical, anthropological/historical,ethnomedical) standards and ways how to quantify ethnopharmacological information. In order to provide a morphological basis for understanding the role of nitric oxide (NO) in the thymus, present study was designed to clarify the localization and distribution of nicotinamide adenine dinucleotide phosphate-diaphorase (NADP-d) activity, a marker of NO synthase in rabbit and rat thymuses. Soluble P-selectin, SELP polymorphisms, and atherosclerotic risk in European-American and African-African young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. The TGIF mRNA and protein expressions were statistically significantly higher in the leiomyoma compared with the matched, unaffected myometrial tissues in both phases of the menstrual cycle. Study of Pseudomonas phascolicola phage 525 and its nucleic acid by an electron microscopic method. We demonstrate, as proof-of-concept, 2.5 Gbps reconfigurable optical interconnects between an 850nm vertical cavity surface emitting lasers (VCSEL) array and a photodiode (PD) array integrated onto a PCB by driving two Opto-VLSI processors with steering and multicasting digital phase holograms. Neurosensory testing was performed prior to surgery, and at 2 weeks, 1 month, 3 months, 6 months, and 1 year following surgery. These data suggest that multiple pathways, one of which is ER-stress induced, may ultimately be involved and interactive in the induction of apoptosis in specific cell lines.

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In cultured mouse podocytes triptolide pretreatment prevented the puromycin-induced disruption of the actin cytoskeleton and microfilament-associated synaptopodin while protecting nephrin and podocin expression. Expression of the fusion gene FIP1-like 1/platelet-derived growth factor receptor alpha (FIP1L1/PDGFRalpha, F/P) and dysregulated c-kit tyrosine kinase activity are associated with systemic mastocytosis (SM) and chronic eosinophilic leukemia (CEL)/hypereosinophilic syndrome (HES). Here, we summarize the known biological functions of Eph receptors and ligands focusing on the developing nervous system, and we review the data on possible mechanisms of action. Inferior subluxation of the humeral head after trauma or surgery. The component of the electric field parallel to the gel and membrane surfaces that results from this arrangement may be considered fixed at each position in the gel bed but increases with the decreasing depth of the buffer filled channel below. The lenticular nucleus was gradually shifted to a posterior location. Values of the liquor findings as an indication for a contrast study of suspect lumbar protrusion of the intervertebral disk. No change of the gait disturbance after VCR was noted in seven patients in whom the diagnosis of NPH was not confirmed. The 22- and 50-kHz calls have distinct and mostly non-overlapping acoustic parameters, which ensure unambiguous recognition of the calls and thus, the state of the emitter.

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Effect of hypothermia and cardiac arrest on outcome of near-drowning accidents in children. Gall stone dissolution with methyl tert-butyl ether: how to avoid complications. We promote a more integrated research approach that links molecular physiology of receptor neurons to the ecology of odorants. These values place Galicia as an important isoprene emitter power in Spain as a consequence of the extension of its forests more than of the climatic conditions. Occupational--medicine studies on the dynamics of perchlorethylene in the organism. The cost effectiveness of opportunistic chlamydia screening in England. Experimental and clinical studies on talampicillin in otorhinolaryngology. A simple resection with termino-terminal anastomosis was made with uneventful postoperative course. Loci on the first (c1) and second (c2) chromosomes interact, both positively (c1) and negatively (c2), respectively, such that c1 represses c2 which in turn represses c3.

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MEPM cells were transfected with the plasmid pEGFP-N1 using two non-viral methods: nucleofection and lipofection. Stability was quantified in terms of the within-subject standard deviation (sigma(w)) of BOLD signal changes across measurements. The histopathological study found fungus hyphal without mucosa invasion and the molecular study determined DNA to be Phialemonium curvatum, an unusual pathogen. Clinical significance of levels of molecular biological markers in zones of invasive front-line of colorectal cancer. The main outcome measures were radiological and histological findings. Study on the purification of growth hormone-like substance from pituitaries of the snake Ptyas mucosa. These relationships persisted even after controlling for several variables. Spinal anaesthesia and non-invasive positive pressure ventilation for hip surgery in an obese patient with advanced chronic obstructive pulmonary disease. Within our cohort of competitive athletes, overhead sports and female gender are associated with significantly lower DASH scores and sports module scores. Arteriovenous-shunt-mediated increase in venous return causes apparent right coronary arterial autoregulation.

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PPP (up to 40 mcg/ml) did not affect contractions induced by 5-hydroxytryptamine, suggesting the presence of discrete receptor sites in the blood vessels for different pharmacologically active compounds. Postencephalitic hemiparkinsonism: clinical imaging correlation. Using an original device including cryoprobes and a measurement apparatus to evaluate bioelectrical impedances, the authors have accurately determined the zone of irreversible cellular injury after cryotherapy. Here, glutathione S-transferase (GST) pull-down, coimmunoprecipitation and yeast two-hybrid experiments identified beta-tubulin as a novel RAMP1-interacting protein. In this article special attention is given to bleeding, which is the most common pyridium 200 tablet uses complication in this field. The mdm2 gene is frequently amplified in human sarcomas, which may be responsible for the malignant transformations. The presence of UDP-N-acetylglucosamine:alpha-3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I activity in Spodoptera frugiperda cells (IPLB-SF-21AE) and its enhancement as a result of baculovirus infection.

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The existence of contact-dependent secretion in Chlamydia strongly suggests that these bacteria use pathogenic mechanisms that are similar to those of other intracellular bacterial pathogens. An invasive urothelial bladder tumour was discovered in a 62-year-old man, 3 months after a 2nd renal transplantation. Bovine erythrocytes taken from in vitro cultures of Babesia bovis parasites from Mexico and the United States were assayed for the presence of new epitopes on the erythrocyte surface. This article reviews the literature on emerging bacterial resistance in ophthalmology, and summarizes the AFSSAPS guidelines. In rumen fluid, the concentration of NH3 N was lower for ryegrass that was fertilized with the low amount of N. Subjects with RA have significantly increased periodontal attachment loss compared to controls. The patient had not a past medical history of nosebleeds and laboratory parameters were within normal ranges. Interestingly, in the field of multidisciplinary simulation, the problem of model exchange between different simulation tools occurred much earlier. Comparative studies on the influence of radioprotectors and amino acids on the chromosome-damaging valium normal dose range activity of 8-hydroxyquinoline sulfate in human lymphocytes in vitro.

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We postulate that genotype, systemic metabolic conditions, and local tissue interactions establish the level of local tissue mechanical stimulation (attractor state) appropriate for the maintenance of bone tissue. Amino acid residues essential for biological activity of a peptide derived from a major histocompatibility complex class I antigen. Sensing bitter or odorous substances on a synthetic lipid multibilayer film by using quartz-crystal microbalances and electric responses. Patients with stab wounds show lower incidence of this complication. Standard large numerical aperture wide field or scanning optical systems are not capable of the large field of view and detection sensitivity required to collect fluorescence from parallel arrays of microfluidic devices.

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