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Alnacob (Gabapentin)
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Alnacob

Alnacob is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve pain where it blocks pain by interfering with pain signals travelling through the damaged nerves and the brain.

Other names for this medication:
Alcobal, Alnacob, Cobimep, Comago, Encentin, Gabacian, Gabaciz, Gabamin, Gabaneuron, Gabantin, Gabapin, Gabastar, Gabata, Gabaz, Gabil, Gabufast, Gapen, Gentin, Hyteron, Malzix, Mecobal, Mecogab, Mecomed, Mecona, Mecoriv, Mecova, Melife, Metgaba, Nervibrain, Nervoday, Nervoptin, Nervuptin, Neuronti, Neuropill, Nexcob, Nurokind, Nuromark, Nuvolt, Orogab, Progaba, Wintin, Zintigo

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Also known as: Gabapentin

Description

Alnacob (gabapentin) is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Alnacob is used in adults to treat neuropathic pain (nerve pain) caused by herpes virus or shingles (herpes zoster).

Alnacob is also used to treat seizures in adults and children who are at least 3 years old.

Use only the brand and form of gabapentin your doctor has prescribed. Check your medicine each time you get a refill to make sure you receive the correct form.

Dosage

Generic Alnacob is available in tablets, liquid form and capsules(300 mg, 400 mg). The dosage of Generic Alnacob depends on the type of your disease and health state. Take Generic Alnacob tablets, liquid form and capsules orally at the same time every day with water. Generic Alnacob can be used together with other seizures medicines. Take Generic Alnacob 3 times a day with or without food. If you want to achieve most effective results do not stop taking Generic Alnacob suddenly.

Overdose

If you overdose Generic Alnacob and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alnacob overdosage: feeling drowsy, double vision, slurred speech, diarrhea, difficulties with breathing, problems with coordination.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Alnacob are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Alnacob if you are allergic to Generic Alnacob components. Do not take Generic Alnacob if you are pregnant, planning to become pregnant. Avoid breast-feeding. Be careful with Generic Alnacob if you are taking morphine (such as MSIR, Avinza, Kadian), hydrocodone (in Vicodin, in Hydrocet), naproxen (such as Anaprox, Aleve, Naprosyn). Generic Alnacob can be used together with other seizures medicines. Be very careful with Generic Alnacob if you suffer from or have a history of heart, kidney or liver disease. Be careful with Generic Alnacob if you are going to have a surgery. Children should be very careful with Generic Alnacob because it can cause changes in behavior. If you experience drowsiness and dizziness while taking Generic Alnacob you should avoid any activities such as driving or operating machinery. Avoid alcohol. It can be dangerous to stop Generic Alnacob taking suddenly.

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RECONSTRUCTION OF PATHOLOGICAL DISLOCATIONS OF THE HIP JOINT IN CHILDREN WITH CAPSULAR ARTHROPLASTY. Rapid regulation of a cyclic AMP-specific phosphodiesterase (PDE IV) by forskolin and isoproterenol in LRM55 astroglial cells. TGF-beta isoform and receptor expression in giant cell tumor and giant cell lesions of bone. The data are independent of conventional findings on MRI and potentially useful in characterising and demonstrating the architecture of vascular lesions of the brain. However, we believe that conducting a large population screening for every cancer susceptibility gene (e.g.

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jejuni 81-176 flagellin were subjected to capillary liquid chromatography-electrospray mass spectrometry with a high/low orifice stepping to identify peptide segments of aberrant masses together with their corresponding glycosyl appendages. Evaluation of renal biopsies in type 2 diabetic patients with kidney disease: a clinicopathological study of 216 cases. Barnase-conjugated pig transferrin was prepared by the periodate oxidation procedure. Langerhans cell histiocytosis of an adult with tumors in liver and spleen. The causative agents of these diseases, termed prions, consist of the host-encoded prion protein (PrP).

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Oligo(trimethylene carbonate)-poly(ethylene glycol)-oligo(trimethylene carbonate) triblock-based hydrogels for cartilage tissue engineering. Mutations in all of the CP motifs of Bach1 abolished its interaction with heme. Insurance data for research in companion animals: benefits and limitations. CONCLUSIONS/RELEVANCE TO CLINICAL PRACTICE: Nurses need to be alerted to the necessity of documenting early signs of deterioration of patients, particularly the respiratory rate. We reviewed the electronic health records of 500 patients with scleritis, 35 of whom were diagnosed with herpes virus infection, seen at 2 tertiary referral centers. By gene set enrichment analysis, we identified the cell-cycle pathway and its member polo-like kinase 1 (Plk-1) to be significantly overexpressed in primary melanomas and in melanoma metastases. In this study, we present three patients treated for 4 years with i.v. Isolation and characterization of novel giant Stenotrophomonas maltophilia phage phiSMA5. One of the possible prophylactic methods is increasing the concentration of butyrylcholinesterase in the blood with the simultaneous administration of butyrylcholinesterase reactivators, when the enzyme is continuously reactivated by oxime. Mechanisms for defining supercoiling set point of DNA gyrase orthologs: II.

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This model is used as a tool for testing for violations of M and IIO. Involvement of hepatic metallothioneins in hypozincemia associated with bacterial infection. The first aim of this study was to evaluate the in vitro efficacies of fluconazole, ketoconazole, itraconazole and voriconazole on M. Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats. Personal interviews of 12 pharmacists from community and academic practice settings about monitor preference, as well as results from a national survey of pharmacist recommendations, were compared to actual wholesale sales data to estimate the impact of such recommendations on final monitor selection by the patient.

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Endogenous Ca content in whole embryos and its localization in Golgi regions of skeletogenic cells was strongly reduced, as measured by atomic absorption spectrometry and in vivo calcein labeling. Regulation of ANP clearance receptors by EGF in mesangial cells from NOD mice. Concurrently binding and delivering this combination of molecules is cumbersome, because of the opposing supramolecular host requirements. Nature of the regulation of cardiac rhythm in repeated exposure to neuro-emotional stimulus. Scaffolds with various pore sizes and porosities were developed by varying braiding angle which was controlled by the gear ratio of the microbraiding machine. In this study, we develop a method for network-based analysis of genetic associations (NETBAG). In the first stage the underlying hazards and between-study variance are estimated using the marginals, while a second stage is used to estimate both within-arm and between-arm correlations. The result reflects the directional information of the measured objective surfaces. Magnetic resonance imaging revealed a cystic lesion in the sacrum compressing the nerve roots.

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Ultrasound (US) imaging and measurement have been widely used for the assessment of articular cartilage (AC) in recent years. Complications of cardiac catheterization in adults and children with congenital heart disease in the current era. Molecularly targeted therapies in unresectable-metastatic gastric cancer: a systematic review. We conducted comprehensive gene expression profiling with wild-type and p45-null megakaryocytes and examined the functional relationship between p45 and Nrf2. The retention time could be reduced significantly by increasing the flow-rate, while the capacity factor remained at the same level. This is the first evidence suggesting unconditional female dominance in a cheirogaleid primate. In addition, we find that the AS types can be classified into two general classes, namely the exon skipping related process (ESRP), and the alternative splice site selection process (ASSP), based on their association levels with the epigenetic features. Objective and subjective assessments of Kodak Ektaspeed plus new dental X-ray film: a comparison with other conventional X-ray films. Spleen-preserving laparoscopic distal pancreatectomy would be an ideal approach for benign and borderline malignant tumors in the distal pancreas.1 However, this procedure requires advanced surgical experience and technique because of the disadvantages of conventional laparoscopic surgery.2. Recent investigations indicate that excess actions of FGF23 cause several hypophosphatemic diseases whereas deficient FGF23 activity results in hyperphosphatemic tumoral calcinosis.

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Such accelerated changes in session impact may reflect the suggested acceleration of therapeutic change associated with shorter time limits. But, perindopril significantly decreased ACE activity in brain without affecting its mRNA expression. In an effort to reduce morbidity and recovery time, an endoscopic technique was used for the management of this condition. In one case, many larvae of the black soldier fly, Hermetia illucens L. This anisotropic polarization state of the light emitted from the probe was compensated for by using a Berek compensator placed in front of the fibre coupler. Radiolytic degradation of the herbicide dicamba for environmental protection. With different imaging techniques we came to the correct diagnosis, a partial abnormal pulmonary venous return, which was surgically confirmed. We isolated cDNA clones for two nuclear-encoded, organellar members of the Arabidopsis hsp70 gene family, mtHsc70-2 (AF217458) and cpHsc70-2 (AF217459).

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One-hundred and fifteen untreated consecutive women diagnosed as having PCOS. This effect was fully prevented by pre-incubation with the sodium channel blocker tetrodotoxin and was partially inhibited by the two nicotinic receptor antagonists methyllicaconitine (MLA) and dihydro-beta-erythroidine (DHbetaE). Conditioned place preference (CPP) paradigm has been used to test ethanol (EtOH) rewarding properties after repeated (20 days) injections of EtOH. Inhibition of inspiratory activity occurs at a higher PaCO2 during PLV than during GV in cats with surfactant-depleted lungs. Frequent central venous catheter access and multiple endomyocardial biopsies appear to predispose to infection. The method has been conceived to be amenable to the high-throughput screening of mutants in order to unravel the molecular mechanisms involved in the interaction between yeasts and host phagocytes. Jewish and Catholic ethics of reproduction: converging or standing apart?.

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Cytogenetic and molecular analysis showed an interstitial deletion in the long arm of the paternally derived homologue of chromosome 13 (13q14.2-13q22.2), which encompasses the retinoblastoma and Wilson disease loci. We report a case of rapidly involuting congenital hemangioma of the flank, which was diagnosed in the 2(nd) trimester of gestation and showed complete involution before term. Lichen scrofulosorum is a tuberculid that is usually seen in children or young adults. The data indicates that mice, unlike several other species, are more resistant to vitamin E depletion and may have other mechanisms to compensate for loss of this important antioxidant. Some other authors describe immediate full weight-bearing after osteosynthesis with the same implant. We believe that patients with isolated thrombocytopenia should be tested for the presence of aPL antibodies, as our findings have shown a correlation between the presence of aPL antibodies and occurrence of TE events. Measures of public and private self-consciousness and negative affect were administered and assessments of past and current smoking behavior were obtained. Ochratoxins have been reported also as a natural contaminants in many spices.

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N100m to tones was larger in the right hemisphere, whereas that to speech sounds was bilaterally similar. The mathematical formulation of this theory on the basis of the mass law is described. High efficient removal of mercury from aqueous solution by polyaniline/humic acid nanocomposite. Results of subjective tests to assess the acceptability and naturalness of the synthetic laughter relative to real human laughter samples are presented. During further growth intermittent exit block occurred, first misinterpreted as neurological seizures. The cell culture system using HCV-permissive Huh-7.5 cells make studies on interaction of NK cells and HCV-infected target cells possible. Many treatments have been advocated but only surgery and radiotherapy have had some success. In 10 of these dogs MPG was infused locally into a small side branch of the LAD in a dose of 0.15 mg kg(-1) min(-1), starting 10 min prior to and continuing throughout the entire PC procedure. In vivo and transgenic animal models used to study visceral hypersensitivity. The purified enzyme, like the bulb enzyme, preferentially accepted tuliposides as substrates, with 6-tuliposide A the best substrate, which allowed naming the enzyme tuliposide A-converting enzyme (TCEA), but specific activity and molecular mass differed between the petal and bulb enzymes.

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Effective interventions to prevent and treat depression in youth exist, but their therapeutic benefit appears to be, on average, small, possibly due to the clinical heterogeneity subsumed under the current diagnostic construct of depressive disorder. Since the nanoliter droplet never touches the sample container wall, any possible extraction of contaminants adsorbed on the plastic or glassware is avoided. In the present Hypothesis article, we summarize and present data from the literature that support our hypothesis on the potential mechanisms by which UPS (ubiquitin-proteasome system) inhibitors reduce I/R (ischaemia/reperfusion) injury in the liver. The degree of radiosensitization by transfection of DPYD siRNA was similar to that of gimeracil. This can be achieved, as was shown by Arvind Kumar, who, in his PhD project, generated monoclonal antibodies to cross-reacting yet neutralising epitopes of a number of rhinoviruses. Representative isolates were assigned to 37 multi-membered and 107 single membered colour groups based on their ability to form pigments on oatmeal and peptone yeast extract iron agars.

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Effects of gel concentration, human fibronectin, and cation supplement on the tissue-engineered cartilage. This is a study of peripheral cells which do not express all of the Na,K-ATPase expressed in the brain. For the prevention of osteoporosis, it is important to consume sufficient Ca and to maintain and appropriate Ca/P balance from diet. Intracellular Virus Trafficking Reveals Physiological Characteristics of the Cytoskeleton. Of other pathogens, only coccidian oocyts were inconsistently but concurrently detected with BoCV. These data are consistent with the observation in women that long-term use of oral contraceptives or multiple pregnancies significantly increases the risk for cervical cancer in HPV-positive women. Proteins with PDZ domains bind to PDZ-binding motifs almost exclusively when the motifs are located at the carboxyl (C-) terminal ends of their binding partners. Organochlorine pesticide residues in sediment and fish samples collected from the east and west coasts of India are presented. Effect of previous how much does nexium usually cost experience of a hurricane on preparedness for future hurricanes. In boys, a possible association between phimosis, LSA and HPV has been suggested.

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Assessment and impact of microbial fecal pollution and human enteric pathogens in a coastal community. A taxonomic treatment of the Camellioideae at the tribal level is also proposed. The simulation module is validated by comparing the results of experimental measurements made on artificially illuminated algal suspension with those predicted by the Monte Carlo program. A microfluidic device with integrated fluorimetric detection for flow injection analysis. We think the recurrence in our case was due to totipotent multicentricity of the tumor. We have shown here that the selected enhancer motif promotes exon inclusion through specific interaction with SRp30. Intrinsic and apparent stability constants of metal-adenine nucleotide complexes.

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All patients received an hour of therapy three times a week for six weeks administered by the same physical and occupational therapists. PROCEDURES FOR RAPID AND IN-SERIES ANALYSIS OF THE COMMON BARBITURATE DERIVATIVES. To assess whether there are significant differences in ease of use and quality of samples among several bone biopsy needles currently available. The results suggest that electrical activity of the neural pathways from the HPC to ME are very dependent on the excitability of the HPC, whereas those from the AMYG to ME seem variable, depending on the activity of the AMYG. We used systematic methods to identify studies for inclusion, assess methodological quality, and abstract relevant data about study design and results. M1775R induced unusual, thread-like promyelocytic leukemia (PML) nuclear bodies and clustered RPA foci rather than the typical juxtaposed RPA-PML foci seen with wild-type BRCA1.

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The analysis of mouse embryos constitutively lacking Gli3 has revealed the essential GLI3 functions in specifying the anteroposterior (AP) limb axis and digit identities. The coincidence of the recognition temporal thresholds and occurrence of differences in the visual EPs suggests that the temporal characteristics of these processes differ in different subjects. Discordance between the molecular data and previous morphology-based subgeneric classifications are noted. To test their contribution at the network and the behavioral level, we generated genetically modified mice in which the excitatory drive was selectively reduced either by the knockout of the GluR-D or by conditional ablation of the GluR-A subunit in parvalbumin-positive cells. Copper deficiency in the laying hen resulted in anemia and the production of eggs which were abnormal in size and shape. The cycle ends when the portal tide slowly diminishes and acinar volume is back on the interphase value until the new perfusion cycle is started in another circulatory unit. Phosphorylated PRL (PPRL) is considered to be the most important posttranslationally modified form in the rat.

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Kinetics of appearance of four hemorphins from bovine hemoglobin peptic hydrolysates by HPLC coupled with photodiode array detection. The biological activity of NO is acutely terminated by oxidation to nitrite and nitrate, and these compounds have long been considered only as inert end-products of NO. This proves that the membrane potential is due to the establishment of a membrane equilibrium and that the powdered particles participate in this membrane equilibrium. Effect of zinc and its form of supply on production and quality of coffee beans. Intermediate followup of hand assisted laparoscopic nephroureterectomy for urothelial carcinoma: factors associated with outcomes. Gross and microscopic tissue analysis was performed to assess lesion size and renal parenchymal, collecting system and arterial effects. Variations in accuracy, relating to differences in plasma specific gravity and in hemoglobin, were demonstrated.

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Critical care physicians are proponents of early, aggressive, multifaceted therapy. Stellate cells undergo a process known as activation, in response to any insult. A cross-sectional survey was carried out in 1989 in urban area of the city of Tianjin, China. A beneficial effect of increased number of EPC in compliant individuals, in relation to weight loss, was observed. In this paper the pathogenesis, epidemiology, skin and organ manifestations of the disease were presented. An increase in glycinergic quantal amplitude and frequency during early vestibular compensation in mouse. A computerized BAE system has been developed and some experiments have been conducted. We aim to use nanocrystal formulation as a way to circumvent the difficult solubilization practice. We aimed to identify the expression and phosphorylation status of PTEN, PI3K and downstream signaling in MPM. Fractional genomic alteration detected by array-based comparative genomic hybridization independently predicts survival after hepatic resection for metastatic colorectal cancer.

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After fertilization, the message remains in most animal blastomeres. Additionally, a number of aspects of PARP function were measured. Ultrasound can replace radiographic studies and thereby reduce radiation exposure to the young infant. Twelve patients with primary squamous cell carcinoma of the breast pathologically confirmed were retrospectively reviewed. Anesthesia in pediatric patients may be different than in adults due to the specific anesthesia considerations in children, notably the propofol infusion syndrome (PRIS) and the need to monitor immature neural pathways. The mesodermal expression in the B region is located in the anterior region of each segment, as defined by the position of ganglia in the ventral nerve cord, and is involved in the morphogenesis of hydrea segment-specific feeding structures late in larval life.

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One of ostrich (Struthio camelus) trypsinogen genes was cloned from pancreatic cDNA. New analogs of somatostatin: inhibiting effectively GH, glucagon and insulin levels. Gentamicin-resistant Klebsiella infections in a neonatal intensive care unit. We propose that the proteasome-ubiquitin pathway may be involved in the peripheral quality control of other, partially unfolded membrane proteins as well. The two groups were similar at baseline, and no clinically significant changes in these parameters were seen during the observation time. In contrast, a C-terminal peptide from Cdc42 neither bound nor diamox medication class activated AGAP1. While rare mutations in the early-onset genes (amyloid precursor protein, and presenilins 1 and 2) lead to increased generation of specific forms of the amyloid beta protein (A,beta), common polymorphisms in the late-onset genes (apolipoprotein E and alpha 2-macroglobulin) are thought to alter the clearance and degradation of A,beta in brain. In addition, we showed that nitric oxide inhibits purified ornithine decarboxylase by S-nitrosylation. An increased number of autophagosomes and autophagic vacuoles have been observed in cystinotic fibroblasts and renal epithelial cells, suggesting that altered autophagy plays a role in NC, leading to increased production of reactive oxygen species. Although there is overlap in clinical features between MKS and BBS, MKS patients are not obese and do not develop retinopathy or have learning disabilities.

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For liver surgical planning, morphology and topology analysis of the hepatic vessel system is of our major interest. These changes in chromatin are now at the forefront of research in the field of oncogenesis, both as mechanisms of oncogenesis and as prognostic indicators of cancer risk. It therefore requires a comparison between a pre-exposed (PE) and a non-pre-exposed (NPE) condition. In addition, although IL-1ra levels are elevated in most of the TMD patients, the increases do not appear to be sufficient to inhibit the inflammation and connective tissue degradation associated with IL-1beta. Severe renal failure associated with proteinuria occurred in a 21-year patient, who had massive rheumatic aortic regurgitation. Data were gathered on 201 subjects through a self-report survey instrument and analyzed through structural equation modeling. Actin was degraded slowly, but no liberated fragment could be detected. The knowledge of clinical decision criteria, algorithms, and standards of patient care are essential for the acceptance within a trauma team. The short PANAS scale represents a good and practical alternative for the original version, with lower but still acceptable internal consistency values. The economic costs of NIHL have been estimated to be billions of dollars.

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The Nature and Significance of the Bohr Effect in Mammalian Hemoglobins. uPAR is central to several pathways implicated in tumor progression and angiogenesis. We describe here the case of silica particles covered by zebeta 6 or 7 layers of polyelectrolyte multilayers. The sample size is 5,826, including 642 respondents with physical disabilities. In female cattle mean values for IGF-I varied from 5.1 nmol/l in postparturient Holstein cows to 18.5-20.5 nmol/l in growing beef heifers, while mean IGF-II concentrations ranged from 30.0 nmol/l in the cows to 14.7-15.7 nmol/l in the beef heifer calves. In addition, the validation and the determination of analytical error were also described.

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NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain. Scleral buckle (SB) removal is rarely performed due to extrusion, infection, or diplopia. Cut-off values for left ventricular hypertrophy were 134 g.m-2 for males and 102 g.m-2 for women. A hospital based case descriptive study of MS patients, seen at Sultan Qaboos University Hospital in the Sultanate of Oman, between June 1990- June 2000. These findings were also observed in group C rats, except that there was hyperinsilinaemia. Quasistatic drag force and pressures at the bottom and the side wall are measured simultaneously. The results clearly demonstrate the potential advantages offered by this approach. Thus, recent advances in understanding how checkpoints in the cell cycle work at the molecular level open the door to new approaches to antitumor therapy. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. Ad-S37A was injected into the vitreous of normal rats to activate the Wnt pathway in the retina.

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