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Alpam (Alprazolam)

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Alpam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Acalm, Alpam, Alpanol, Alpkair, Alprasert, Alprocontin, Alproz, Altin, Alzam, Alzep, Alzocum, Alzot, Anilam, Anxilam, Anzocalm, Calmtec, Cozac, Depser, Depsolam, Dizeral, Elflu, Emlol, Endep, Enxolam, Erazol, Ezoprax, Fluwel, Fultop, Hipose, Hiprazole, Mcalm, Omelam, Onapract, Optizole, Plxna, Prazil, Proprazolam, Resta, Samprex, Somnirest, Tenschem, Tensyl, Tranisol, Trazopin, Trustin, Visram, Welnorm, Zallpam, Zolar, Zolent

Similar Products:
Urispas, Starlix, Vantin, Aldara, Clozaril, Thorazine, Normadep, Purgoxin, Canditral, Uticina, Lorfast, Cynomycine, Topgesic,

Also known as: Alprazolam


Alpam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alpam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alpam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alpam or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alpam. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alpam with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alpam. Ask your doctor how to avoid withdrawal symptoms when you stop using Alpam.

Keep track of the amount of medicine used from each new bottle. Alpam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpam XR dosage information

Side effects

The most common side effects associated with Alpam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Obliteration is progressive after radiosurgery of cerebral arteriovenous malformations. The isolation and identification of ubiquitin from the high mobility group (HMG) non-histone protein fraction. RTX treatment may induce sustained remission in patients with GD with low TRAb levels. Understanding the composition and structure of the basement membrane provides insight into the pathophysiology of inherited blistering disorders, such as epidermolysis bullosa, and acquired bullous diseases, such as the pemphigoid group of autoimmune diseases and epidermolysis bullosa acquisita. To examine the effects of changing physical environment on the occurrence of sclereids in petals, sclereid density in petals of six species, including wild samples from different rainfall zones and samples from a greenhouse under mild conditions without wind and rain, were examined and statistically analysed. Psychiatry has to play a more active role in planning and performing these programs. Gastric retentive delivery systems potentially allow increased penetration of the mucus layer and therefore increased drug concentration at the site of action. Her family history revealed that her only son had cystic fibrosis. Patients with rheumatoid arthritis (RA) develop both periarticular and generalized osteoporosis.

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Biological and molecular characterization of lettuce mosaic virus from Tehran province in Iran. Treatment of HepG2 cells with PPARalpha and LXR synthetic agonists also blocks the inhibition of apoA-I protein secretion in HepG2 cells under the impact of TNFalpha. Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) affect angiogenesis differently during embryogenesis and tumorigenesis. Role of the N- aygestin 5 mg bid terminal region for the conformational stability of esterase 2 from Alicyclobacillus acidocaldarius. Two patients developed severe retinopathy with vision loss to counting fingers and hand motions without resolution of the retinopathy. Intraoperative small bowel enteroscopy in familial adenomatous and familial juvenile polyposis. Blinded, controlled field trial of two commercially available Mycoplasma bovis bacterin vaccines in veal calves. Evaluation of syndromic management of sexually transmitted infections in Saudi Arabia.

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We evaluated pathological features in a large series of stage pT1 conventional renal cell carcinoma cases and examined the association of these features with cancer specific survival. Although several European countries have already interrupted indigenous MV transmission, genotyping showed that 3 endemic MV transmission chains have been reestablished in other countries. Knowledge of the criteria for treatment restorations and the adequacies of their construction is essential for the prevention of catastrophic failures, patient management problems, and compromised results. MRI is the method of choice for imaging of muscle abnormalities. They are located preferentially in the lower part of the head of the pancreas. Questions remain as to which of these structures best represents PTSD, how the structure changes with time, the applicability of models to returning veterans, and the validity of the symptom clusters. The correct diagnosis was made during surgery for an asymptomatic gallstone. Satraplatin: leading the new generation of oral platinum agents. These spectroscopic studies have permitted the determination of ligand-specific high-spin states which reveal similarities and differences between iNOS and nNOS. The nascent peptide is concluded to pass through a tunnel that extends about 100 A between the peptidyl transferase center and its exit site.

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Mechanisms of cellular recruitment in aseptic loosening of prosthetic joint implants. The isoprenoid modification was detected in p67 isolated both from primary IFN-gamma-activated macrophages and when the gene for p67 was transfected into COS cells. Here, we expand on the previous work to develop new tools and strategies for 1) better visualizing synaptic ribbons, and 2) monitoring and manipulating calcium on the synaptic ribbon. The authors presented their preliminary experience in diagnosis, surgical technique and satisfactory outcome. This should be considered when choice of drug and prophylaxis is being made. BIOPSY STUDY OF THE CAPILLARIES OF THE SKIN IN THE DIABETIC PATIENT. We present the endoscopic and echoendoscopic findings of two patients with secondary linitis plastica of the rectum. We used logistic regression on ordered data to assess the influence of vulvovaginal candidiasis on the HIV-1 load in cervicovaginal secretions adjusting for potential confounders. A number of clinical studies have found a good relationship between concentration and pharmacologic response and/or toxicity as well as wide interpatient variability in the pharmacokinetics of protease inhibitors.

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We have observed that exposure of U937 cells, pre-incubated for 18 h with 0.2 microM hypericin, to 599 nm laser radiation with a fluence of 2.5 J/cm(2) renders them insensitive to higher light doses. This prospective multi-center trial investigated whether the quality of treatment can be improved by self-management in patients with atrial fibrillations (SMAAF Study) compared to conventional patient management by the family doctor. baumannii infections in ICU patients due to the potential for developing resistance. A three-meal-a-day dietary pattern versus ad libitum food intake in the albino rat. These vectors facilitate the directional cloning of DNA encoding a peptide of interest at or near the N terminus of the major coat protein, the product of the bacteriophage gene VIII, and the construction of hybrid capsids in which the modified coat protein is interspersed with wild-type coat protein subunits. Immuno-gold labelling of isolated viral particles and electron microscopy demonstrated the incorporation of TGN46, endosomal markers early endosomal antigen 1, annexin I, transferrin receptor and CD63, and the cation-independent mannose 6-phosphate receptor, which traffics between the TGN and endosomes into the viral envelope. In response to combined cidofovir and antiretroviral therapy he showed significant clinical improvement. Though insufficient evidence on other outcomes is available from randomised trials, the increased fixation failure rate is a major consideration and thus the SHS appears preferable.

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To help delineate the possible role of IL-4 in such maternal tolerance, female mice genetically deficient in IL-4 were studied. 143 patients with 143 SMTs of the EGJ originating from the muscularis propria layer. Topoisomerases constitute a family of highly conserved essential enzymes, which exist in all investigated living pro- and eukaryotic cells. Electron microscopic observation of nucleosomes in ultrathin sections of heparin-treated nuclei. Diagnostic ultrasound is one of useful and noninvasive tools for clinical medicine. This study demonstrates the anatomic feasibility of an anterior window laryngoplasty as an alternative approach to treating posterior glottic stenosis while preserving the cartilage framework and avoiding the anterior commissure. This uncommon finding presented as a symptomatic paratracheal mass that was resected using thoracoscopic techniques without complication. In this work, we introduce a threshold-free analysis approach for sparse and highly heterogeneous datasets obtained from cultures of sensory neurons. This is a single-center study conducted in a cancer-specialized ICU in Brazil. Finally, different approaches that incorporate protein dynamics, e.g., configurational entropy, and solvation effects into docking will be highlighted.

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Echocardiographic features of congenital pulmonary regurgitation. The albino A/J strain was selected because it had the most amount of ageRD among several inbred strains tested, and the pigmented C57BL/6J strain was selected because along with its coisogenic counterpart C57BL/6J-c(2J) it had the least amount of ageRD. TWO SUBCLASSES OF MOUSE 7S GAMMA-2-GLOBULINS: GAMMA-2A- AND GAMMA-2B-GLOBULINS. Under local anesthesia 600 microns laser-fibers were inserted by stereotactic-guided technique into the center of the tumor. The objective of this study was to determine if mifepristone, a glucocorticoid receptor antagonist, could prevent olanzapine-induced weight gain. Invasive and noninvasive methods of assessing adriamycin cardiotoxic effects in man: superiority of histopathologic assessment using endomyocardial biopsy. This species is geographically restricted to only three islands of the Ryukyu Islands and is on the federal list of threatened plants. Leg length discrepancy in total hip arthroplasty with the use of cemented and uncemented femoral stems.

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