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Alpkair (Alprazolam)

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Alpkair is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpkair, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpkair is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Aderta, Alpaz, Alpranex, Alprasert, Alprine, Alprop, Alzep, Alzoact, Anilam, Anxiflu, Anxigon, Apsolam, Axnil, Belfa, Calmef, Coolam, Cooltime, Esteem, Faxtin, Fluxin, Golprax, Hipose, Maxorest, Nokzok, Notens, Omelam, Orten, Pecalm, Pifzot, Pranol, Prazil, Prolam, Prozam, Pyrex, Resolin, Resto, Richpram, Rivcam, Rozin, Silam, Suzilam, Tancalm, Tenrid, Tenschem, Tensyl, Zolark, Zolipax, Zolorel, Zopral

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Prevacid, Theolair, Lasix, Precose, Lodine, Cialis, Wormicid, Canibioprim, Belpro, Empeea, Antiworm, Konokold, Pantakind, Lasilactone, Ignis, Ubiphene,

Also known as: Alprazolam


Alpkair is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alpkair is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alpkair if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alpkair or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alpkair. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpkair. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alpkair for medical reasons, the best way to avoid a Alpkair overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpkair consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpkair XR dosage information

Side effects

The most common side effects associated with Alpkair are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol while taking Alpkair XR. This medication can increase the effects of alcohol. Alpkair XR can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Grapefruit and grapefruit juice may interact with Alpkair XR and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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We identified a missense mutation within a novel open reading frame in the rc/rc mice, which is predicted to encode a cell adhesion molecule with the highest homology to myelin protein zero (MPZ) and myelin protein zero-like 2 (MPZL2, also called epithelial V-like antigen). The procedure also has immune potentiating effects, perhaps by promoting peripheral suppressor mechanisms. We present the case of a 20-year-old female with a history of spontaneous abortion 1 year prior. For each method, model equations were derived (for an arbitrary N-pool system), tested via simulation studies, and validated via experimental studies in an aqueous urea model system. Metabolite profiling and identification in human urine after single oral administration of DEHP. This simplified exercise score that estimates the probability of CAD can be easily applied without a calculator and is a useful and valid tool that can help physicians manage patients presenting with chest pain. Unfolded-state structure and dynamics influence the fibril formation of human prion protein.

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Some putative etiologic factors, mainly amalgam restorations and hepatitis C virus, have been studied in detail. Thirty two binge drinkers and 53 controls (non binge drinkers), with no history of other drug use, personal or family history of alcoholism or psychopathological disorders, were selected. Pairs of haplotypes from single populations were frequently more divergent than haplotypes sampled from widely disjunct populations. Cystic adventitial disease of the popliteal artery: a recurrent case after cyst wall excision . The latest library contains 78 new reviews, 10 of which are considered relevant to practitioners in pain and palliative care. For this retrospective case series of patients with occupational hand injuries, case records were retrieved to gather data. In 3 healthy subjects the left tibial nerve was electrostimulated at the ankle.

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Tangible and social reinforcers for correct responses in assessing severely retarded school-age children. The problem of using an explicit representation of time in diagnostic systems is analyzed and recent work on the different characterizations of diagnosis arising when the temporal dimension is considered is reported. We show that Nep1 can deneddylate the Pcu1, Pcu3 and Pcu4 cullins in vitro and that its activity is sensitive to N-ethylmaleimide, consistent with the idea that it is a member of the cysteine protease family. However, a contrary conclusion was obtained with clinical specimen, a higher positive rate of KISS1 expression being displayed in osteosarcoma patients, especially in metastastic cases, compared to the benign osteochondroma patients. There is substantial experimental evidence to support the view that Ginkgo biloba extracts have neuroprotective properties under conditions such as hypoxia/ischemia, seizure activity and peripheral nerve damage. The amount of ferrocyanide formed when denatured egg albumin reacts with ferricyanide in the absence of Duponol PC depends on the temperature and ferricyanide concentration throughout the whole range of ferricyanide concentrations, even in the low range of ferricyanide concentrations in which ferricyanide does not react with amino adds other than cysteine. The diameters of the anterior belly digastric fibers in normal mice fed only a granulated diet were smaller than those in mice fed a solid diet.

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Characteristics of surgical treatment of chronic suppurative lung diseases in the Extreme North (Yakutsk). Muscle architecture was studied in 12 specimens and revealed that the long head of the triceps is better suited for forearm reconstruction than either the gracilis or the latissimus dorsi muscles. Eight patients, seven men and one woman, average age 23 years (range 18-34), with multi-level brachial plexus injuries were selected for transplantation using either cadaveric allografts or living-related donors. This patient had been in Vietnam and Laos several years previously and, while there, developed a flu-like syndrome. Consequently, the 5a-reductase inhibitor finasteride was developed and has proven efficacious in promoting hair growth as a consequence of lowering scalp and plasma dihydrotestosterone levels. We applied the lectin-affinity electrophoresis and antibody-affinity blotting techniques to HCC patients in Vietnam in order to better understand the role of lentil lectin-affinity AFP-L3 in the diagnosis and differential diagnosis of HCC, and its relationship with the biological characteristics of HCC. The results and side effects before and 2 weeks after the colposcopic re-examination were recorded.

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To investigate the cost-effectiveness and cost-benefit of a lifestyle intervention for construction workers with an elevated risk of cardiovascular disease. Variations in microsatellite sequences provide evidence for population differences and multiple ribosomal gene repeats within Trichinella pseudospiralis. Therefore, intranasal (i.n.) immunization of 3 doses 1 week apart with AFCo1 plus PsC in mice was conducted. The efficacy of barrier precautions to prevent influenza transmission is unknown. A CASE OF APLASIA OF THE STAPEDIAL MUSCLE AND THE EMINENTIA PYRAMIDALIS. Eighty-two percent of requests were approved, and approval could be predicted by the week of gestation and the reason for application. The effect of obliquity on the radiographic appearance of the temporomandibular joint in dogs. Cellular, endocrine and metabolic signals that flow bidirectionally between the vasculature and bone are necessary for both bone health and vascular health. One had developed focal motor epilepsy which was considered to be unrelated to his previous attack of micturition syncope. Future pharmacological treatment options for nonexudative and exudative age-related macular degeneration.

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The fluorescence quantum yields for both isolated molecule and aggregation are predicted to be insensitive to temperature due to the hydrogen-bonding nature, and their values at room temperature are consistent with the experiment. The two sites of renal COX-2 localization detected in all species to date are the macula densa (MD) and associated cortical thick ascending limb (cTALH) and medullary interstitial cells (MICs). However, if food was returned to the rats 6 h after 2DG injection, they still ate significantly more than after saline control injections. After GSC treatment, HT-29 cells became smaller and irregular in shape. Our results have implications on the iron-dependent regulatory mechanism of M.tuberculosis vis-a-vis the activity of urease operon and novel transcription regulators and transporters. Blood fungal cultures in this case remained negative, suggesting that molecular assays may facilitate the laboratory diagnosis of disseminated histoplasmosis.

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The first reports of the New Influenza A (H1N1) spoke of a markedly increased morbidity and mortality. Survey of Australian parents and primary care givers of children 0-15 years. To assess the outcome of patients, who underwent transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and subsequently liver transplantation (OLT) irrespective of tumor size when no tumor progression was observed. The discovery that mutations in the TK domain are associated with dramatic and sustained responses to EGFR rocaltrol 0 25 mg TK inhibitors (TKIs) has allowed the design of trials to test these agents as potential first-line therapies and has provided a fascinating window into the future of genotype-directed targeted therapy. The objective of the present study was to determine the effect of replacement of fat by sucrose polyester (SPE) within a lunch or evening meal on subsequent energy intake and appetite control. The accumulation of visual purple in the retina after bleaching by light has been studied in the intact eye of the frog. Substantial isoprene emissions were observed from thirty-one species, including Caryota mitis, Adenanthera pavonina var. Using administrative health data for the surveillance of interventions for alcohol-related harm among young people.

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When autosomal short tandem repeats fail: optimized primer and reaction design for Y-chromosome short tandem repeat analysis in forensic casework. Exploring sexual problems among patients with multiple sclerosis. Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression. A fluorescent screen is viewed by a low light level Isocon television camera and the video signal is digitized and stored. This study has identified the level of independence for the A and M skills needed by new DPT graduates, provided empirical evidence suggesting which A and M skills should be included in DPT curricula, and suggested a pattern of A and M skill acquisition that applies first to the new therapist and the patient, then to the organization, and finally to the health care environment. The learning and memory abilities of the mice in Morris water maze test and the mechanisms involved in the neuroprotective effect of yam on the mice brain tissue were investigated. Trivia-psychotica: the development and evaluation of an educational game for the revision of psychiatric disorders in a nurse depakote medication child training programme. Hepatitis B vaccination has been recommended for injection drug users (IDUs) since 1982, but vaccination coverage of IDUs remains low (1), and outbreaks of hepatitis B among IDUs continue to occur.

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Thirty-one male and female subjects consumed 3 x 250-mL servings of a beverage containing green tea catechins, caffeine, and calcium for 3 days in a single-center, double-blind, placebo-controlled, cross-over design study. To determine whether taxadienol or the corresponding acetate ester serves as the direct precursor of subsequent oxygenation reactions, microsomal preparations isolated from induced Taxus cells and optimized for cytochrome P450 catalysis were incubated with each potential substrate. Additional evaluation included color fundus photography with FA and ICG, OCT analysis of vasotec 5 mg oral tablet the macula and B-scan ultrasonography. Three-dimensional structure of scaffolding-containing phage p22 procapsids by electron cryo-microscopy. Each participant also performed 4 different tasks designed to assess source memory. In the other four stems, the bone lacked continuity with the surrounding trabecular bed. However, a distance of ca 5 A separates the catalytic water molecule from the acyl carbonyl group of meropenem, a structural feature that accounts for the inhibition of OXA-13 by this drug.

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Further investigations are needed to explore whether the relationship is causative. To assess and compare, prospectively, schizophrenia relapse in relation to neuroleptic medication in long term maintenance therapy. The difference between the conductivity of the mixture and the sum of the conductivities of the components alone passes through a maximum at a pH theoretically calculable as the isoelectric point of the system. Psychomotor disadaptation syndrome: a poorly known clinical entity. Here we review the important features of the Cav1 channelopathies.

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ALTERATIONS IN BANKED BLOOD, WITH SPECIAL REFERENCE TO HEMOSTASIS. Participants were scanned using functional magnetic resonance imaging while watching short video clips of threatening actions and performed either color or emotion judgments. Student teams solve practical projects solicited from faculty, industry and the local community. The formation of triclinic structure might be validated due to the partial polymerization of FNWs at C(60) saturated CS(2)-IPA interface. Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain-like protease?. In the SSS posterior occlusion group (SPO group) the ligation was performed close to the confluence sinum. Measurements of saturator effluent air concentrations, saturator efficiency and precipitated are reported for both cold water and warm water operating conditions.

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