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Alpostin (Alprostadil)

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Alpostin is used to treat erectile dysfunction (impotence) and to help diagnose certain causes of this disorder. Alpostin is also used to improve blood flow in newborn babies with heart problems. This medication guide addresses only the adult male use of Alpostin in erectile disorders.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


Alpostin injection is used to treat certain heart, lung, and blood vessel problems in infants. It is used to temporarily keep the ductus arteriosus (blood vessel in the heart) open before having a surgery.

This medicine is to be given only by or under the supervision of your child's doctor.

This product is available in the following dosage forms:

  • Solution


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For urethral dosage form (suppositories):
    • For erectile dysfunction:
      • Adults—One suppository inserted into the urethra once a day, 10 to 30 minutes before sexual intercourse. Do not use more than 2 suppositories each day.
      • Children—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose can cause fainting, or a painful and prolonged erection.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store unopened foil pouches in the refrigerator. Keep the medicine away from heat. It may not work if exposed to temperatures above 30 degrees C. You may also store the suppositories at room temperature for up to 14 days before each use.

Detailed Alpostin dosage information

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The most common side effects associated with Alpostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to Alpostin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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