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Ioglime (Pioglitazone)

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Ioglime is a diabetes drug prescribed alongside diet and exercise to control blood sugar levels in people with Type 2 diabetes. A thiazolidinedione, or glitazone, Ioglime may be used alone or with other diabetes drugs.

Other names for this medication:
Accuglim, Amaryl, Diamet, Diazero, Glimestar, Glimsite, Glito, Glitter, Glizone, Glucut, Glufit, Glyciphase, Ioglime, Matce, Mepride, Metride, Mopady, Pianorm, Pioglu, Piolet, Pioplus, Pioryl, Piozol, Piozone, Radizone, Triblend, Triexer, Trigem, Triglaz, Triglimiprex, Vedapride, Walaphage, Ziglim

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Also known as: Pioglitazone


You should take Ioglime according to your doctor’s or healthcare provider’s instructions.

Ioglime comes as a tablet that you swallow.

When to take

You’ll take Ioglime once a day. Try to take this medication at about the same time each day.

Don’t take more than one dose in a day.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Taking Ioglime with food

You can take Ioglime tablets with or without food.

Can Ioglime be crushed, split, or chewed?

No, you shouldn’t break, crush, split, or chew Ioglime tablets. Broken tablets haven’t been studied, so it’s not known if it’s safe to take a tablet that’s broken.

If you’re having trouble swallowing your Ioglime tablets, talk with your doctor. They may be able to suggest ways to help you take your medication or recommend other drugs that may be easier for you to take.


Usual Adult Dose for Diabetes Type 2:

-Patients without congestive heart failure: Initial dose: 15 mg or 30 mg orally once a day -Patients with congestive heart failure (New York Heart Association [NYHA] Class I or II): Initial dose: 15 mg orally once a day Maintenance dose: 15 mg to 45 mg orally once a day based on glycemic response as determined by HbA1c Maximum dose: 45 mg orally once a day Comments: -This drug exerts its antihyperglycemic effect only in the presence of endogenous insulin and therefore is not expected to be effective in patients with type 1 diabetes mellitus or diabetic ketoacidosis. -Patients concomitantly receiving an insulin secretagogue or insulin may need to reduce the dose of the insulin secretagogue or insulin if hypoglycemia occurs. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings

Detailed Ioglime dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Ioglime are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Ioglime if you are allergic to pioglitazone, or if you have:

severe or uncontrolled heart failure; or diabetic ketoacidosis (call your doctor for treatment).

This medication may increase your risk of developing bladder cancer. Talk with your doctor about your specific risk.

To make sure Ioglime is safe for you, tell your doctor if you have ever had:

congestive heart failure or heart disease; a heart attack or stroke; eye problems caused by diabetes; bladder cancer; or liver disease.

Ioglime may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. Talk to your doctor about the risks and benefits of this medicine.

Follow your doctor's instructions about using Ioglime if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

Pioglitazone may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

Women may be more likely to have a broken bone while using Ioglime. Talk with your doctor about ways to keep your bones healthy.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Ioglime is not approved for use by anyone younger than 18 years old.

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