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Myotan (Losartan)

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Myotan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily. It is taken by mouth. It may be used alone or in addition to other blood pressure medication.

Other names for this medication:
Angioten, Corodin, Covance, Gitox, Hilos, Hypozar, Lavestra, Loben, Losacar, Losapot, Losart, Losatrix, Losazide, Losium, Lotan, Medzar, Ostan, Portiron, Rosatan, Sartens, Sarve, Sortiva, Stadazar, Tensartan, Tensiohess, Xartan, Zaart, Zartan

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Also known as: Losartan


Myotan is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Myotan is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Myotan is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Myotan reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease


Take Myotan tablets orally with or without food. Do not crush or chew it. Take Myotan once or twice a day at the same time. If you want to achieve most effective results do not stop taking Myotan suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Myotan are:

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Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Myotan.

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Fluorescence microscopy revealed a close correlation among actin stress fiber formation, cell contraction, and FN binding. The mutation substitutes a tyrosine for the first of seven highly conserved cysteine residues in the mature active domain of the protein. We suggest that the progressive diaphyseal dysplasia gene has a function in endochondral bone formation and that its mutation is a dynamic one with repeat expansion enhanced in father-to-son transmission. Concentration of lactates in venous blood in patients with stroke. Bradykinin facilitates the purinergic motor component of the rat bladder neurotransmission. The effect of ortho substitution on the mass spectral fragmentation of polychlorinated biphenyls. Identification of loss-of-function mutations of SLC35D1 in patients with Schneckenbecken dysplasia, but not with other severe spondylodysplastic dysplasias group diseases. Despite the 2.5 times higher pour-on dose, this formulation did not result in excretion of detectable concentrations of ivermectin over a longer period of time than did the injection treatment. The output THz power variation with wavelength can be properly explained with a decrease of parametric gain and the spectral profile of absorption coefficient of GaSe. Phosphorylation of serine 264 impedes active site accessibility in the E1 component of the human pyruvate dehydrogenase multienzyme complex.

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Antibodies against stress proteins in sera of patients with dilated cardiomyopathy. Our data do not lend support to a role for Sf1 in the regulation of aromatase expression during slider turtle sex determination, but do support a critical role for estrogen in ovarian development. Thus, by inducing active death of endothelial cells oxidized low-density-lipoprotein might negatively influence tissue homeostasis of the endothelium and thereby promote the development of atherosclerotic plaques. Study subjects received cefazolin 15-60 minutes prior to incision and controls received cefazolin at the time of cord clamping. We identified 14 unique CSP sequences in expressed sequence tag (EST) libraries of the red imported fire ant, Solenopsis invicta. When an antibody was present, the LIS medium invariably gave stronger, more clear-cut results.

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The treated plants with GA(3) showed an increase in HMGR activity. Nucleotide substitutions and small-scale insertion produce size and antigenic variation in group A streptococcal M1 protein. Furthermore, as previously observed in RIN-5AH cells, a predominant expression of the long form of PRL receptor vs. Hereby, the reduced glutathione and reduced ascorbic acid contents are higher in NahG plants under salt stress. A neuropsychological assessment of the effects of moderate marihuana use.

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Intraabdominal calcification in treated disseminated carcinoma of the ovary. Based on pulse-chase experiments, it appears that at least 3 of the large polypeptides (140,000, 65,000, and 50,000 daltons) are precursors to the three major internal structural polypeptides of the mature virions. Purification of human intrinsic factor by affinity chromatography. No further recurrences of diarrhea or colitis were encountered while the patient was taking Saccharomyces boulardii and for 18 months of follow-up after the yeast was discontinued. The ripples present on the input pulse seed the modulation instability at high pump powers, affecting soliton fission. In animals and yeast, ALA is formed in a single step from succinyl CoA and glycine by aminolevulinate synthase (ALA-S) in mitochondria. Short-term administration of celecoxib, 400 mg x day(-1) po, decreased postoperative pain and the need for opioid-containing analgesic medication, leading to an improved quality of recovery after outpatient laparoscopic surgery. Among its different applications, this concept may be used for the correction of inborn errors of liver disease and acute liver failure.

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Delay of gratification in the development of control over risk taking. Macrolides are a group of diverse class of naturally occurring and synthetic antibiotics made of macrocyclic-lactone ring carrying one or more sugar moieties linked to various atoms of the lactone ring. Phenotypic analysis of dengue virus isolates associated with dengue fever and dengue hemorrhagic fever for cellular attachment, replication and interferon signaling ability. A statistical survey of deep mycoses in Japan, with particular reference to autopsy cases of cryptococcosis. Comparisons were by intention-to-treat analysis, using longitudinal models for change in BMD. In this way design tasks which are difficult to accomplish with conventional FFT-based design methods, such as spot positioning at non-sample positions and/or spot positioning in 3D, are solved as easily as any standard design task using a conventional method. Five of the fifteen affected discs were at the level L3/4, eight at L4/5 and two at L5/S1.

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The replication timing of the amplified dihydrofolate reductase genes in the Chinese hamster ovary cell line CHOC 400. First, the viramune generic name large within-person variability of platelet aggregation tests may make the demonstration of any associations difficult, though the study had reasonable power to show effects with ADP. This is the first demonstration of the developmentally regulated appearance of a thymic epithelium specific antigen (not present in other epithelial cells e.g., skin, mucosa). An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA. The ability of the superinfecting bacteriophage to protect the transfecting DNA from inactivation was maximal when the bacteria were just becoming competent.

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METHOD (STUDY SELECTION CRITERIA): Only EUS studies confirmed by surgery were selected. Her sputum examination was positive for Mycobacterium tuberculosis complex by nucleic-acid amplification test, and she was diagnosed as miliary tuberculosis. On ultrasonography and computerized tomography scan, a round tumor about 2.5 cm in diameter in the posterior portion of the right kidney and another tumor about 7 cm in diameter arising from the upper pole of the left kidney. seroquel medication controlled substance Therefore, our data suggest that DREAM appears not to qualify as a target in peripheral pain management. The yields of infiltrating node on tumor surface were the highest (7.24 x 10(5)), in the tumor proper (2.49 x 10(5)), and in the ovarian tissue the lowest (2.07 x 10(5)). Assessment of articular cartilage and subchondral bone: subtle and progressive changes in experimental osteoarthritis using 50 MHz echography in vitro. Rural/frontier nursing research poses unique methodological challenges, including definitional inconsistency, social/cultural issues, methodological/statistical concerns, and the inherent diversity among rural communities.

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