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Solosprin (Isosorbide)

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Solosprin is used to prevent heart-related chest pain (angina). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medicine will not treat an angina attack that has already begun

Other names for this medication:
Aspitrate, Dilatrate, Ecosmin, Ismorin, Ismotic, Isoditrate, Isoloprin, Isordil, Isosorbide, Monit, Monoket, Monosprin, Nitren, Nitrofix, Nitroprin, Solosprin, Vasoprin

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Also known as: Isosorbide


Generic Solosprin is a perfect remedy, which helps to treat angina attacks. Generic Solosprin acts as nitrates. Solosprin is also known as Isosorbide Mononitrate. Generic name of Generic Solosprin is Isosorbide Mononitrate. Brand names of Generic Solosprin are Solosprin, ISMO, Monoket.


This section provides information on the proper use of a number of products that contain isosorbide mononitrate. It may not be specific to Solosprin ER. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This form of nitrate is used to reduce the number of angina attacks over a long time. It will not relieve an attack that has already started because it works too slowly. The extended-release form gradually releases medicine to provide its effect for 8 to 10 hours. Check with your doctor if you also need a fast-acting medicine to relieve the pain of an angina attack.

You should take this medicine first thing in the morning and follow the same schedule each day. This medicine works best if you have a "drug-free" period of time every day when you do not take it. Your doctor will schedule your doses during the day to allow for a drug-free time. Follow the schedule of dosing carefully so the medicine will work properly.

Swallow the extended-release tablet whole with a half glass of water. Do not split, crush, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For prevention of angina: For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Take the dose in the morning right after you wake up. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—20 milligrams (mg) two times a day. Take the first dose in the morning right after you wake up, and the second dose 7 hours later. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of isosorbide mononitrate can be fatal.

Overdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions).


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Isosorbide mononitrate dosage information

Side effects

The most common side effects associated with Solosprin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Solosprin if you are allergic to Generic Solosprin components. Do not take Generic Solosprin if you're pregnant or you plan to have a baby. Do not use potassium supplements or salt substitutes. Be careful using Generic Solosprin if you take dihydroergotamine (D.H.E. 45); or any other heart medicines, especially those used to treat high blood pressure or irregular heartbeats. Be careful using Generic Solosprin if you suffer from or have a history of congestive heart failure, have low blood pressure; a stroke, a transient ischemic attack (TIA, or mini-stroke), have anemia; have an allergy to nitrates; have closed-angle glaucoma; migraines, kidney disease; liver disease, heart attack, a serious head injury. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Do not stop taking Generic Solosprin suddenly.

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Potentialities of traction therapy for diskogenic compressive radicular syndromes. Each inducer produced a characteristically different pattern of enzyme activities with dexamethasone, isoniazid and beta-naphthoflavone selectively inducing erythromycin N-demethylase, p-nitrophenol hydroxylase and ethoxyresorufin O-dealkylase respectively. Mean PEG-IFN alpha-2a (40KD) exposure was dose proportional from 180 to 270 microg week(-1). Our results indicate that Cdk2 is not required for proliferation and differentiation of hematopoietic cells in vivo, although in vitro analyses consider Cdk2 to be a major player in proliferation and apoptosis in these cells and a potential target for therapy. Partial activation of the factor VIIIa-factor IXa enzyme complex by dihexanoic phosphatidylserine at submicellar concentrations. In this study we have used two different mutated viruses containing a truncated TLM and showed their ability to infect human hepatocytes in primary culture, thus demonstrating the dispensability of the TLM for HBV infectivity.

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Rheumatoid lung: pulmonary nodules preceding and accompanying rheumatoid polyarthritis. The efficacy of wearing compression stockings on clinical vessel disappearance following sclerotherapy of telangiectasias and reticular veins has been a matter of debate for half a century. In three subjects there was evidence of disseminated intravascular coagulation that may zantac drug generic and brand name be responsible for aggravating the condition of liver hypoxia. Our data demonstrate that combination treatment with a human GLP-1 analogue and a dual PPARalpha/gamma agonist through distinct mechanism of actions synergistically improves glycaemic control in the ZDF rat. One population of astrocytes is highly capable of cell volume regulation, while the second population is characterized by prominent cell swelling, accompanied by plastic changes in morphology. Synthesis and anthelmintic activity of cyclohexadepsipeptides with cyclohexylmethyl side chains.

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Recent advances in bipolar and obsessive compulsive disorders: nature and treatment. Using TRE-2S as a probe, we screened a cDNA library of HUT102 cells by the Southwestern (DNA-protein) procedure and isolated two cDNA clones, THP-1 and -2. Data were collected from computed tomography scans with use of the Lund-Mackay scale. In comparing cardiovascular risk factors, males differed only in percent of smokers (31.5 in AS vs. The blood system of the flabelligerid polychaete Flabelliderma commensalis (Moore). On the basis of the results thus obtained and the familial nature of these abnormalities, we predicted phenotypically normal fetuses in both cases. An evaluation of the cardiovascular safety profile of duloxetine: findings from 42 placebo-controlled studies. Specificity and mechanism of action of pantothenic acid on intestinal absorption of glucose in rats.

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